17/Dec/2025
Effect of non-invasive ventilation and high-flow nasal cannula on hospital mortality in COVID-19-induced acute respiratory failure: a meta-analysis
einstein (São Paulo). 17/Dec/2025;24:eRW0695.
View Article17/Dec/2025
Effect of non-invasive ventilation and high-flow nasal cannula on hospital mortality in COVID-19-induced acute respiratory failure: a meta-analysis
DOI: 10.31744/einstein_journal/2026RW0695
ABSTRACT Background Non-invasive respiratory support strategies, such as high-flow nasal cannula therapy and non-invasive ventilation, were widely employed during the coronavirus disease 2019 (COVID-19) pandemic, yet their comparative effectiveness remains uncertain. Objective To compare the effects of high-flow nasal cannula therapy, non-invasive ventilation, and conventional oxygen therapy on intubation rates and hospital mortality in adults with COVID-19-related acute respiratory failure. Methods A systematic review and meta-analysis was conducted following PRISMA and Cochrane guidelines, with searches performed in nine databases for […]
Keywords: COVID-19; Intubation; Mortality; Noninvasive ventilation; Oxygen inhalation therapy; Respiratory insufficiency; SARS-CoV-2
31/Oct/2025
Determinants of invasive ventilation in infants with acute bronchiolitis: an observational study of pre-hospital and in-hospital treatments
DOI: 10.31744/einstein_journal/2025AO1512
Highlights ■ This single-center study evaluated the frequency and factors associated with invasive ventilation in infants with acute viral bronchiolitis on a pediatric ward. ■ The study revealed an invasive ventilation rate of 6%, associated with age, presence of atelectasis, and Wood-Downes-Ferres score at admission. ■ Many interventions with poor scientific evidence were used. ■ This study highlights the need to implement clinical protocols for the management of acute viral bronchiolitis, including all levels of care, as these infants are […]
Keywords: Bronchiolitis; Bronchodilator agents; Child; Epidemiology; Hospitalization; Infant; Intubation; Pulmonary atelectasis
10/Jun/2025
Perception of the multidisciplinary team and the patient’s family companion regarding their presence during emergency room care
einstein (São Paulo). 10/Jun/2025;23:eAO0871.
View Article10/Jun/2025
Perception of the multidisciplinary team and the patient’s family companion regarding their presence during emergency room care
DOI: 10.31744/einstein_journal/2025AO0871
Highlights ■ Family presence improves communication and patient comfort during pediatric emergency room care. ■ Overall, 90.2% of companions stayed during care, despite 71% being unaware of the legislation. ■ Of the professionals, 96% allowed companions, with 87% citing comfort for patients. ■ This study supports creating clear protocols for family inclusion during emergencies. ABSTRACT Objective: To evaluate the perceptions of family companions and the professional team regarding the presence of a family member during emergency and urgent care at […]
Keywords: Adolescent; Cardiopulmonary resuscitation; Child; Emergency service, hospital; Hospital, pediatric; Intubation; Intubation, intratracheal; Patient care team; Surveys and questionnaires
20/May/2022
Bronchoscopy in COVID-19 inpatients: experience of a university hospital in the first outbreak of the disease in Brazil
einstein (São Paulo). 20/May/2022;20:eAO6858.
View Article20/May/2022
Bronchoscopy in COVID-19 inpatients: experience of a university hospital in the first outbreak of the disease in Brazil
DOI: 10.31744/einstein_journal/2022AO6858
ABSTRACT Objective: To describe the indications and endoscopic findings of bronchoscopy performed at a reference university hospital for inpatients diagnosed with COVID-19 during the first outbreak of the disease in Brazil. Methods: A retrospective analysis of medical records of adult patients diagnosed with COVID-19 who underwent bronchoscopy at the intensive care units of Instituto do Coração and Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, from March to August 2020. Results: A total of 132 bronchoscopies […]
Keywords: artificial; Betacoronavirus; Bronchoalveolar lavage; Bronchoscopy; Coronavirus infections; COVID-19; intratracheal; Intubation; Respiration; SARS-CoV-2
09/Jun/2015
Risk factors for post-extubation stridor in children: the role of orotracheal cannula
DOI: 10.1590/S1679-45082015AO3255
Objective To determine the risk factors associated with stridor, with special attention to the role of the cuffed orotracheal cannula. Methods Prospective analysis of all the intubated patients submitted to mechanical ventilator support from January 2008 to April 2011. The relevant factors for stridor collected were age, weight, size and type of airway tube, diagnosis, and duration of mechanical ventilation. The effects of variables on stridor were evaluated using uni- and multivariate logistic regression models. Results A total of 136 […]
Keywords: Child; intratracheal/instrumentation; Intubation; Respiratory sounds; Risk Factors
