23/Jan/2020
Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software
DOI: 10.31744/einstein_journal/2020AO5023
ABSTRACT Objective To adapt an antibiotic dose adjustment software initially developed in English, to Portuguese and to the Brazilian context. Methods This was an observational, descriptive study in which the Delphi method was used to establish consensus among specialists from different health areas, with questions addressing the visual and operational aspects of the software. In a second stage, a pilot experimental study was performed with the random comparison of patients for evaluation and adaptation of the software in the real […]
Keywords: Anti-infective agents; Brazil; Dosage forms; Intensive care units; Piperacillin; Software; Surveys and questionnaires
30/Oct/2018
Suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups
einstein (São Paulo). 30/Oct/2018;16(4):eAO4354.
View Article30/Oct/2018
Suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups
DOI: 10.31744/einstein_journal/2018AO4354
ABSTRACT Objective To analyze suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups. Methods A descriptive study of drugs with pediatric indication included in a retrospective cohort of new drugs registered in Brazil. The evaluation of drug suitability for the pediatric age group was performed using the following criteria: suitability of dosage form and capacity to deliver the recommended dose. The drugs were considered adequate for the pediatric age groups when they met both […]
Keywords: Child; Dosage forms; Drug approval; Drug therapy; Reference drugs