All publications of “Cristina Sanches”

4 results

Effective vancomycin concentrations in children: a cross-sectional study

Geisa Cristina da Silva Alves ORCID logo , Farah Maria Drumond Chequer ORCID logo , Cristina Sanches ORCID logo

DOI: 10.31744/einstein_journal/2019AO4396

ABSTRACT Objective Analyze the microbiological effectiveness, based on the pharmacokinetics/pharmacodynamics correlation of vancomycin in pediatric patients, and to propose dose adjustment. Methods This is an observational, cross-sectional study, conducted in a pediatric hospital, over a 1-year period (2016 to 2017). Children of both sexes, aged 2 to 12 years, were included in the study; burn children, and children in renal replacement therapy were excluded. For the pharmacokinetic analysis, two samples of 2mL of whole blood were collected, respecting the 2-hour […]

Is quality of life associated with compliance to pharmacoterapy in patients with chronic kidney disease undergoing maintenance hemodialysis?

Keila Batista Alves, Nathália Vital Guilarducci, Thiago dos Reis Santos, André Oliveira Baldoni, Alba Otoni, Sérgio Wyton Lima Pinto, [...]

DOI: 10.1590/S1679-45082018AO4036

ABSTRACT Objective To analyzed the association of quality of life and compliance to drug treatment in chronic kidney disease patients. Methods The Short Form Health Survey was used to evaluate the quality of life of these patients, and the therapeutic complexity index was verified. The Morisky-Green test and the Brief Medication Questionnaire were applied to check compliance to drug therapy. Results A total of 197 patients were included. The Morisky-Green test and Brief Medication Questionnaire showed that most patients had […]

Compliance and leadership: the susceptibility of leaders to the risk of corruption in organizations

Renato Almeida dos Santos, Arnoldo José de Hoyos Guevara, Maria Cristina Sanches Amorim, Ben-Hur Ferraz-Neto

DOI: 10.1590/S1679-45082012000100003

In the field of organizational management, the term “compliance” designates the set of actions to mitigate risk and prevent corruption. Programs are composed by formal control systems, codes of ethics, educational actions, ombudsmen, and reporting channels – to mention the most recurrent, which vary according to the sector, the institutional culture, and the strategy. Leadership has a fundamental role in the process of compliance, not only due to its power to implement it, but precisely because it exercises this power, […]

Financial incentives for generic drugs: case study on a reimbursement program

Marcos Inocencio, Maria Cristina Sanches Amorim, Arnoldo Jose de Hoyos Guevara, Bruna de Vivo

DOI: 10.1590/s1679-45082010ao1478

ABSTRACTObjective:To discuss the use of financial incentives in choice of medication and to assess the economic results concerning the use of financial incentives to promote the use of genetic medication in lieu of reference drugs in a company with a reimbursement program.Methods:A case study was carried out in a large supermarket. The data was obtained in the company responsible for managing medication. The study reached 83,625 users between August 2005 and July 2007. The data was submitted to regressions in […]