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Transarterial radioembolization (TARE) with yttrium-90 microspheres is a palliative locoregional treatment, minimally invasive for liver tumors. The neoadjuvant aim of this treatment is still controversial, however, selected cases with lesions initially considered unresectable have been enframed as candidates for curative therapy after hepatic transarterial radioembolization. We report three cases in which the hepatic transarterial radioembolization was used as neoadjuvant therapy in an effective way, allowing posterior potentially curative therapies.
Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports
CarvalhoVO, GalastriFL, AffonsoBB, FalsarellaPM, ValleLGM, Ferraz-NetoB, RezendeMB, et al. Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports. Einstein (Sao Paulo). 2020;18:eRC4990. https://doi.org/10.31744/einstein_journal/2020RC4990
Carvalho,Vithor de Oliveira; Galastri,Francisco Leonardo; Affonso,Breno Boueri; Falsarella,Priscila Mina; Valle,Leonardo Guedes Moreira; Ferraz-Neto,Ben-Hur; Rezende,Marcelo Bruno de; Motta-Leal-Filho,Joaquim Maurício da; Garcia,Rodrigo Gobbo; Nasser,Felipe. Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports. Einstein (Sao Paulo)., v. 18, eRC4990, Feb. 2020. https://doi.org/10.31744/einstein_journal/2020RC4990
Carvalho,V.O., Galastri,F.L., Affonso,B.B., Falsarella,P.M., Valle,L.G.M., Ferraz-Neto,B., Rezende,M.B. , Motta-Leal-Filho,J.M. , Garcia,R.G., & Nasser,F. (2020). Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports. Einstein (Sao Paulo).,18, eRC4990. https://doi.org/10.31744/einstein_journal/2020RC4990
Carvalho,Vithor de Oliveira and Galastri,Francisco Leonardo and Affonso,Breno Boueri and Falsarella,Priscila Mina and Valle,Leonardo Guedes Moreira and Ferraz-Neto,Ben-Hur and Rezende,Marcelo Bruno de and Motta-Leal-Filho,Joaquim Maurício da and Garcia,Rodrigo Gobbo and Nasser,Felipe. Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports. Einstein (Sao Paulo). [online]. 2020, vol. 18, [cited 2025-09-05], eRC4990. Available from: <https://journal.einstein.br/article/transarterial-radioembolization-for-liver-tumors-as-neoadjuvant-therapy-three-case-reports/>. ISSN 1679-4508. https://doi.org/10.31744/einstein_journal/2020RC4990
Figure 3
Transarterial radioembolization of the liver before surgery, showing antitumoral and ischemic effect. (A) Computed tomography with volumous suggesting hepatocarcioma on the right hepatic lobe. (B) Computed tomography by positrons emission of immediate control after transarterial radioembolization of the liver showing distribution of Y-90 in the right lobe and segment IV, and lack of uptaking in segment II and III. (C) Tomography reconstruction showing compensatory hypertrophy of left lobe after transarterial radioembolization of the liver. (D) Resected surgical specimen – right lobe and segment IV
Transarterial radioembolization of the liver before surgery, showing antitumoral and ischemic effect. (A) Computed tomography with volumous suggesting hepatocarcioma on the right hepatic lobe. (B) Computed tomography by positrons emission of immediate control after transarterial radioembolization of the liver showing distribution of Y-90 in the right lobe and segment IV, and lack of uptaking in segment II and III. (C) Tomography reconstruction showing compensatory hypertrophy of left lobe after transarterial radioembolization of the liver. (D) Resected surgical specimen – right lobe and segment IV