Ringing a bell in healthcare: harnessing benefits, overcoming implementation challenges, and bridging knowledge gaps of Closed-Loop Oxygen Control systems (CLOCs)

The World Health Organization has listed oxygen as an essential medicine.⁽⁾ Commonly prescribed for hospitalized pediatric and adult patients, there is a wide opportunity to improve its effectiveness by promoting the more rational, sustainable, and safe use of supplemental oxygen.^(,) Guidelines and recommendations for oxygen use may help healthcare workers to adopt and achieve specific oxygen targets,⁽⁾ mitigating hyperoxemia, and hypoxemia.^(,) Staying within safe targets, however, can be challenging, and is also quite time-consuming and labor-intensive, as it requires intensive monitoring and constant manual adjustments of the oxygen flow rate.^(,) Delays in response time, missing care, and human errors are clear challenges⁽⁾ and even short episodes of hypoxemia and hyperoxemia can be critical for specific populations in whom deviations from optimal SpO₂ ranges can occur often and quickly.

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