Stiff-person syndrome (SPS) is an autoimmune disease classically characterized by progressive muscular stiffness and lower back pain with sudden episodes of muscular spasm and, in certain cases, dysautonomia.() In general, the disease is diagnosed based on the presence of high anti-glutamic acid decarboxylase (anti-GAD) antibody titers both in the serum and cerebrospinal fluid (CSF), axial muscle stiffness in the special abdominal and thoracolumbar paraspinal fluid leading to hyperlordosis, painful spasms with well-defined triggers, electromyographic evidence of continuous motor unit activity, […]

We report the case of a 72-year-old patient with stage III breast cancer who presented with multiple pulmonary nodules incidentally detected on computed tomography (CT). Further investigation using positron emission tomography (PET) revealed additional fluorodeoxyglucose-avid (FDG) chest wall lesions and widespread lymphadenopathy (axillary, retropectoral, supraclavicular, pulmonary hilar, and mediastinal), all highly suggestive of recurrent cancer ( and ). […]

A 32-year-old man with renal hyperparathyroidism was referred for surgical treatment after exhausting clinical measures for metabolic control.,Combined analysis of neck ultrasound () and Sestamibi ()/SPECT-CT () findings enabled the identification of three possible enlarged parathyroid glands.The right and left superior parathyroid glands were located in their usual positions beneath the thyroid gland, while the right inferior parathyroid gland was found in the upper mediastinum. […]

A 53-years old white women was presented with a four-weeks history of unsteady gait, followed by mental confusion and progressive memory loss. Neurological examination revealed axial ataxia, short-term memory loss, and brisk deep tendon reflexes in all limbs. Brain MRI () revealed a diffusion signal abnormality involving the bilateral caudate heads and putamen, with no cortical changes. Cerebrospinal fuid (CSF) analysis showed 1 cells per μL, protein content of 25.5 mg/dL, and glucose content of 58 mg/dL. Eletroencefalograma revealed no […]

A 70-year-old man with liver cirrhosis underwent follow-up examinations at our hospital while awaiting liver transplantation. His medical history included an episode of upper gastrointestinal bleeding secondary to the rupture of esophageal varices approximately a year ago. His computed tomography (CT) showed signs of chronic liver disease with subacute portal vein thrombosis, cavernous transformation at the abdominal level, ascites, and right pleural effusion. Furthermore, multiple collateral vessels were observed, some of which ascended through the right hemidiaphragm to communicate with […]

A 42-year-old woman presented with progressive paraparesis; after magnetic resonance imaging of the neuroaxis, an intramedullary tumor was observed at T4-T6 with a syringomyelia and dilatation of the venous system of the posterior fossa. Cerebral angiography revealed dural arteriovenous fistula (DAVF). To treat DAVF, the medullary tumor was surgically resected, and histopathological analysis confirmed the presence of an ependymoma (). The presence of DAVF associated with spinal tumors has not been reported in the literature to date, which makes this […]

Lung cancer represents the most commonly diagnosed neoplasm and the leading cause of cancer-related death worldwide, with majority of the patients being histologically categorized as non-small cell lung cancer. We present the case of a 54-year-old male patient, with a smoking history of 30 pack-years and no other comorbidities, with a pulmonary mass in the left lower lobe () incidentally revealed by computed tomography (CT). After pathological confirmation of adenocarcinoma with hilar lymph node metastasis (cT2b pN1 M0, EIIB), the […]

A 55-year-old male patient presented to the emergency department with ventilatory-dependent chest pain, 5 months after undergoing radiofrequency ablation for atrial fibrillation. Upon initial assessment, the patient exhibited an elevated D-dimer level of 1122ng/mL. Consequently, a computed tomography pulmonary angiogram (CTPA) was requested to investigate because of the possibility of a pulmonary thromboembolism. The CTPA ( ) revealed a focal reduction in the caliber of both the left upper and lower pulmonary veins ostia. Additionally, occlusion of the pulmonary venous […]

A 30-year-old woman had respiratory symptoms and a positive RT-PCR SARS-CoV-2 test. Chest computed tomography (CT) revealed 30-50% lung parenchymal involvement (), suggestive of viral pneumonia. Six days later, she presented with a thunderclap headache, right hemiplegia, and decreased consciousness. CT of the head revealed a large left parenchymal intracerebral hemorrhage (ICH) (), and the patient underwent a decompressive craniotomy. Cerebral angiography showed segmental narrowings followed by dilations in the V2 and V3 segments of the right and left vertebral […]

A 49-year-old woman with a history of pulmonary thromboembolism and right ventricular dysfunction sought consultation with a pulmonologist at our hospital, reporting exertion dyspnea and four episodes of syncope with prodromal palpitations. Physical examination results were unremarkable, and the patient had no history of heart disease. Cardiac magnetic resonance imaging was performed for proper evaluation of the right ventricle. Cardiac magnetic resonance showed normal biventricular function; however, tricuspid valve prolapse and tricuspid annulus disjunction were observed (maximum separation between the […]