09/Aug/2021
Fertility preservation in breast cancer with oral progestin: is it an option? A pilot study
DOI: 10.31744/einstein_journal/2021AO5859
ABSTRACT Objective To compare the effectiveness of oral progestins and injectable gonadotropin-releasing hormone antagonist medication in cancer fertility preservation in patients with breast cancer. Methods A cross-sectional study with 40 breast cancer patients submitted to cancer fertility preservation, who were divided into two groups according to histochemical analysis of progesterone receptors to define luteinizing hormone block: if positive, use of gonadotropin-releasing hormone antagonist, if negative, use of oral progestins. The mean age, medication days, antral follicle count, number of oocytes […]
Keywords: Fertility preservation; Ovulation induction; Progestins; Reproductive techniques, assisted
02/May/2019
Hormone treatment as first line therapy is safe and relieves pelvic pain in women with bowel endometriosis
DOI: 10.31744/einstein_journal/2019AO4583
ABSTRACT Objective: To evaluate clinical features and complications in patients with bowel endometriosis submitted to hormonal therapy. Methods: Retrospective study based on data extracted from medical records of 238 women with recto-sigmoid endometriosis treated between May 2010 and May 2016. Results: Over the course of follow-up, 143 (60.1%) women remained in medical treatment while 95 (39.9%) presented with worsening of pain symptoms or intestinal lesion growth (failure of medical treatment group), with surgical resection performed in 54 cases. Women in […]
Keywords: Contraceptives, oral, combined; Endometriosis/therapy; Hormones/therapeutic use; Pelvic pain; Progestins; Sigmoid diseases; Ultrasonography