26/Feb/2025
Azacitidine-induced bullous pemphigoid-like localized toxic reaction
DOI: 10.31744/einstein_journal/2025RC0699
ABSTRACT Azacitidine is a hypomethylating agent recommended for the treatment of patients with high-risk myelodysplastic syndromes. Here, we report the case of a patient with myelodysplastic syndrome who was not eligible for allogeneic stem cell transplantation (allo-SCT) and presented with a rare and previously unreported cutaneous side effect after the use of subcutaneous azacitidine. We propose that changing the route of azacitidine administration from subcutaneous to intravenous could potentially decrease the occurrence of bullous pemphigoid-like localized toxic reactions in some […]
Keywords: Azacitidine; Myelodysplastic syndromes; Pemphigoid, bullous; Skin diseases
23/Jan/2020
Myelodysplastic syndrome: validation of flow cytometry multilineage score system
DOI: 10.31744/einstein_journal/2020AO4966
ABSTRACT Objective To validate multilineage score system correlating results of flow cytometry, cytogenetics, cytomorphology and histology from samples of patients with suspected myelodysplastic syndrome or cytopenia of unknown origin. Methods A retrospective study analyzing laboratory data of 49 patients with suspected myelodysplastic syndrome or cytopenia of unknown origin, carried out between May and September 2017. The inclusion criteria were availability of flow cytometry results, and at least one more method, such as morphology, histology or cytogenetics. Thirty-eight patients were classified […]
Keywords: Cytogenetics; Cytomorphology; Flow cytometry; Histology; Multilineage score system; Myelodysplastic syndromes