11/Oct/2023
Determining reference ranges for immunological cells of healthy indigenous individuals from a region in Brazil
einstein (São Paulo). 11/Oct/2023;21:eAO0291.
View Article11/Oct/2023
Determining reference ranges for immunological cells of healthy indigenous individuals from a region in Brazil
DOI: 10.31744/einstein_journal/2023AO0291
Highlights The relative medians of CD3+, CD4+, and CD8+ T cells were significantly higher in women than in men in a healthy indigenous population. Demographic and ethnic diversity of the Brazilian population can be associated with quantitative modifications in the immunologic cells of healthy individuals. Objective: The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development. In Brazil, indigenous people are vulnerable to infections, and few […]
Keywords: Antibodies; Brazil; Health Services; Immune system; indigenous; Indigenous peoples; Lymphocytes; monoclonal; Monocytes; Reference values
19/Mar/2020
Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors
DOI: 10.31744/einstein_journal/2020AO5294
ABSTRACT Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis. Methods Regulatory T cells were isolated from peritoneal fluid of women with and without endometriosis, collected during surgery, and mRNA was extracted for analysis of Toll-like receptors expression by reverse-transcriptase polymerase chain reaction. Results Patients with endometriosis presented regulatory T cells expressing a larger number and variety of Toll-like receptors when compared to regulatory […]
Keywords: Endometriosis; Immune system; T-lymphocytes, regulatory; Toll-like receptors
01/Oct/2014
Serum level of vitamin D3 in cutaneous melanoma
DOI: 10.1590/S1679-45082014AO3090
Objective To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital. Methods The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software. Results A total of […]
Keywords: Calcifediol; Cholecalciferol; Immune system; Melanoma; Receptors, calcitriol; Vitamin D deficiency