Highlights ■ HPV+ is associated with improved overall survival in oropharyngeal cancer ■ HPV+ tumors tend to recur earlier than HPV- tumors. ■ Metastasis is a key prognostic factor for mortality and recurrence regardless of HPV status. ■ Smoking and alcohol consumption reduce the favorable prognosis of HPV+. ABSTRACT Objective: To analyze the overall and disease-free survival of patients with oropharyngeal squamous cell carcinoma. Methods: Sociodemographic and clinical data, HPV status, and alcohol/tobacco consumption were assessed among patients treated at […]

Highlights ■ Prevalence of HPV16 is extremely low in the tonsil of healthy Brazilian population. ■ The prevalence of HPV16 in oropharyngeal squamous cell carcinoma was 10% in Brazilian samples. ■ The rate of HPV16 tonsillar infection should be lower than that reported previously in Brazil. ABSTRACT Objective: This study aimed to determine the prevalence of human papillomavirus (HPV) 16 infection in the tonsils of patients without cancer and to analyze the associated risk factors in a low-risk population in […]