Highlights ■ Outpatient palliative care follow-up increased median survival by 4.7 months in patients with advanced head and neck cancer. ■ Patients receiving palliative care had fewer intensive care unit deaths, less chemotherapy in the final month of life, and a reduced need for palliative sedation. ■ Integrated palliative care resulted in fewer emergency visits per month of follow-up, suggesting more efficient symptom management. ABSTRACT Objective: To evaluate whether integrated palliative care is associated with improved overall survival and better […]

Highlights PRKAG2 syndrome is a rare autosomal dominant glycogen storage disease characterized by cardiac hypertrophy, ventricular pre-excitation, and conduction system disease. The rare variant p.K291I in PRKAG2 is associated with poor prognosis, highlighting the need for early intervention. Early diagnosis and intervention using antiarrhythmic drugs, anticoagulants, pacemaker implantation, radiofrequency catheter ablation, and cesarean surgery may improve symptoms and survival rates. The potential connections among intellectual disability, miscarriages, and neonatal deaths in individuals with this syndrome should be further investigated. ABSTRACT […]