2 results
19/Dec/2022
DOI: 10.31744/einstein_journal/2023AO0100
Highlights Karyotype was normal in 60% of patients and altered in 40%. The variants most often detected in the myeloid panel were: JAK2 (54%), ASXL1 (50%), TET2 (31%), and CALR (22%). The median follow-up of transplant patients was 2.4 years and the two-year overall survival was 80%. ABSTRACT Objective To analyze the karyotype test and myeloid panel with next-generation sequencing findings in patients with myelofibrosis, and to compare transplant characteristics in patients referred for bone marrow transplantation. Methods Retrospective, […]
Keywords: Bone marrow transplantation; Cytogenetic analysis; Mutation; Primary myelofibrosis; Prognosis
01/Apr/2011
DOI: 10.1590/S1679-45082011AO1853
ABSTRACT Objective: To identify how the Brazilian hematology centers treated and diagnosed cases of acute myeloid leukemia in 2009. Methods: An epidemiological observational multicenter study of 11 listed Brazilian centers that treat acute myeloid leukemia and perform bone marrow transplantation. Data were collected from clinical charts of patients with acute myeloid leukemia treated at the said centers between 2005 and 2009. The availability for immunophenotyping and cytogenetic tests was assessed. Results: During 2009, a total of 345 new cases of […]
Keywords: Acute myeloid leukemia; Brazil; Cytogenetic analysis; Molecular diagnostic techniques; Therapeutics