1 results
31/Jan/2014
31/Jan/2014
DOI: 10.1590/S1679-45082013000400009
OBJECTIVE: To analyze the immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenomas and non-neoplastic mucosa. METHODS: 72 individuals were subjected to colonoscopy, which provided 50 samples of adenomas and 45 samples of non-neoplastic colorectal mucosa. The tissue samples were obtained via the tissue microarray technique and subjected to immunohistochemical analysis using primary anti-p53, anti-COX-2, and anti-caspase-3 antibodies. The positivity and intensity of the immunoreaction were classified. The analyzed variables were as follows: site of the adenomas in […]
Keywords: Adenoma; Caspase 3; Cyclooxygenase 2; Gene, p53; Immunohistochemistry; Intestine, large