Highlights From the One Health approach, empathy represents the initial movement towards achieving planet harmony. The more emotions we attribute to animals, the more we develop pro-conservation behaviors. AES-Brazil may serve as a tool for reflection and monitoring interventions in human-animal relationships. ABSTRACT Objective: To design and validate a Brazilian version of the Animal Empathy Scale, based on the existing Portuguese version. Methods: Content validity assessment was performed by expert judges, and the adapted scale was administered to a sample […]

ABSTRACT Alternative methods to the use of animals in research have been a global trend, mainly after the publication of the 3R’s principle (Replacement, Reduction, and Refinement), proposed by Russel and Burch. In the cosmetic sector, safety and efficacy assessments using animals have generated controversial debates. For this reason, in vitro research techniques are widely used to assess acute toxicity; corrosivity and irritation; skin sensitization; dermal and percutaneous absorption; repeated dose toxicity; reproductive toxicity; mutagenicity and genotoxicity; carcinogenicity; toxicokinetic studies; […]