einstein (São Paulo). 24/Jun/2024;22:eAO0462.

Is the colposcopic lesion size a predictor of high-grade lesions in young patients?

Beatriz Mokwa dos , Edward Araujo , Rita Maira

DOI: 10.31744/einstein_journal/2024AO0462

Highlights

The size of colposcopic lesions appears to be directly related to lesion severity.
The size of the lesion is directly related to the severity of the histopathological findings in patients ≥25 years old.
The size of the lesion is directly related to the severity of the cytopathological findings in patients aged ≤24 years.

ABSTRACT

Objective:

This study aimed to evaluate whether severity changes with colposcopic lesion size, regardless of age.

Methods:

This retrospective comparative study reviewed the records of 428 women with altered cytopathology reports who were directed by primary health care. Only those women with colposcopic alterations were evaluated (n=411). Histopathological analyses were restricted to patients who underwent excisional treatment (n=345). According to their age, they were grouped into the following: <21, 21–24, 25–35, and >35 years, and also, ≤24 and ≥25 years. The cytopathological, colposcopic, and histopathological findings were grouped according to severity. Lesion size was subjectively assessed from the colposcopic drawing recorded in the chart and according to the number of quadrants of the total cervical surface affected by colposcopic alterations in the transformation zone. Statistical significance was set at p<0.05.

Results:

The evaluations suggested that the lesion size was directly related to the severity of the cytopathology, colposcopy, and histopathology reports for the age groups ≤24 or ≥25 years. We observed associations between lesion size and severity of the cytopathology (≤24 years, p=0.037) and histopathology (≥25 years, p=0.003) findings.

Conclusion:

The size of the lesion was directly related to the severity of the histopathological lesion in patients aged ≥25 years and cytopathological in patients aged ≤24 years.

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Is the colposcopic lesion size a predictor of high-grade lesions in young patients?
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