einstein (São Paulo). 17/Jun/2019;17(3):eED4979.
The role of the doctor in precision medicine
DOI: 10.31744/einstein_journal/2019ED4979
Every day doctors face issues related with identical diagnoses and treatments that generate different outcomes. Being able to individualize care is an old desire of medicine. In this context, precision medicine takes into account individual genetic variability, environmental factors and lifestyle of each individual to find the best therapeutic and preventive approaches for specific groups.() Approximately 15 years ago, the discussion about precision medicine took a new direction due to the new computational technologies and advances in molecular biology that allowed a massive growth in the amount of data.()
In general, individuals seek health care when they perceive that their usual state of health is compromised. Physician gather information and, based on clinical findings and their personal technical knowledge, make decisions about best treatment and preventive measures for the patient. In a setting including precision medicine, patient’s clinical information is collected using electronic medical record since birth, social networks indicate their habits and lifestyle; their electronic devices monitoring vital signs and moves at every second; whole genome brings 2 million different variants, besides the possibility of broaden the application of omics with transcriptome, metabolome and microbiome. All these information are processed using mathematical algorithms and they are used to establish standards and determine treatments, and preventive measures. In the same way that the algorithm can identify cats and dogs pictures, such mathematical algorithms can also identify groups of newborns at risk for hypertension, diabetes, autism.()
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