Highlights ■ The learning curves for robotic peripheral arterial interventions were short, with optimal procedure and fluoroscopy times and radiation emission achieved after the 3rd procedure. ■ There were no differences in learning curves in relation to previous experience or main focus of work. ABSTRACT Objective: This study tests a suitable model for training robot-assisted peripheral vascular interventions and examines the learning curves of endovascular surgeons with different levels of previous experience and main focus of work, analyzing procedure time, […]

Highlights ■ The electronic health record is the first step in digital transformation. ■ Change Management is essential to support problems identification. ■ Identifying and stratifying negative impacts within the staff’s daily routine is crucial. ■ A new method was created, and the method’s effectiveness was evaluated. ABSTRACT Objective: Identify potential negative impacts arising from implementing an electronic medical record system, classify them according to the level of criticality, and analyze method’s effectiveness after implementation. Methods: The research involved identifying […]

Highlights ■ Probability of infection with a high SARS-CoV-2 viral load depends on mask-wearing habits. ■ The higher probability of infection with high viral load occurs for individuals that don’t use mask regularly [47.3%–79.8%]. ■ For individuals who use masks regularly, the probability is 38.6%–52.1%. ABSTRACT Objective: Previous studies indicated that face masks reduce the probability of infection by SARSCoV- 2 but did not examine the relationship between SARS-CoV-2 viral load and mask usage. This study analyzed this relationship. Methods: […]

Highlights ■ The MCM8 gene is involved in homologous recombination, acting in the ovarian follicles during meiosis II. ■ To the best of our knowledge, this is the first study to report the presence of this variant in a Brazilian woman. ■ The rs138761187 variant had a low incidence; further studies with a larger sample size or focusing on variants at other gene positions may provide insight into the genetic causes of premature ovarian insufficiency. ABSTRACT Introduction: The MCM8 gene […]

Highlights ■ Mechanical ventilation and mortality rates remained stable. ■ The birth rate at <28 weeks’ gestation increased during the evaluation period. ■ The overall rate of dexamethasone administration was low; however, its use was more significant in infants aged <28 weeks. ABSTRACT Objective: To evaluate temporal trends in the use of dexamethasone for the treatment of bronchopulmonary dysplasia in very-low-birth-weight preterm infants. Methods: A cohort study was conducted using an electronic database and medical records of all very low-birth-weight […]

Highlights Herbal medicinal product use was 3.8%, with high formal prescription; however, it is accompanied by a high risk of interactions and redundancy. Unified Health System pharmacies are not the main source of herbal medicinal products, suggesting low service implementation. Women, people with mental disorders, and allopathy simultaneously users should receive attention. Non-white people are less likely to use herbal medicinal product, suggesting inequalities in accessing these treatments. ABSTRACT Objective: To determine the prevalence and factors associated with herbal medicinal […]

Highlights Hand reanimation for finger flexion during total paralysis remains a reconstructive challenge. Few surgical options are available for the late presentation of total paralysis of the hand and wrist. Functional freemuscle flap or transfer of the recovered biceps to the long flexors of the digits and flexor pollicis longus may be the last resort. Each case should be evaluated individually to select the best surgical option. ABSTRACT Objective: Hand reanimation for finger flexion in patients with total paralysis remains […]

Highlights The number of vessels was reduced in the placental villi of pregnant women with diabetes. The placental villous vessels of women with previous diabetes were more distant from the maternal blood. ABSTRACT Objective: This study was conducted to investigate the distribution of placental villous vessels in pregnant women with different degrees of hyperglycemia. Methods: A cross-sectional study was performed using placental samples from 30 pregnant women without diabetes (n=10), with gestational diabetes mellitus (n=10), and with previous diabetes (type […]

Highlights Telemonitoring reduced hospital readmissions in patients enrolled in the diabetes program by 15.4%. Men patients who received telemonitoring had lower readmission rates than those who did not. There was a difference in the readmission rate between those who underwent telemonitoring and those who did not in patients aged <60 and >75 years. Patients who stayed >10 days and underwent postdischarge telemonitoring had a lower readmission rate than those who did not undergo telemonitoring. ABSTRACT Objective: To assess whether post-discharge […]

Highlights Tofacitinib use did not result in meaningful changes in hematological parameters. Tofacitinib use did not lead to clinically meaningful changes in liver enzymes. ABSTRACT Objective: Tofacitinib, an oral Janus kinase inhibitor, has been tested against a placebo in 289 patients with COVID-19 pneumonia. We analyzed the data from the tofacitinib- and placebotreated patient cohorts to evaluate the laboratory profiles between baseline and day 7. Methods: We performed post hoc analyses on the following laboratory tests over time during the […]