Highlights ■ First Brazilian Portuguese version of the LT-QOL questionnaire. ■ Translation and cross-cultural adaptation followed COSMIN recommendations. ■ Strong internal consistency (Cronbach’s alpha=0.86). ■ Excellent intra-rater reliability (ICC=0.93). ■ High convergent validity with SF-36 and good correlation  with SGRQ. ■ Provides a disease-specific tool for assessing quality of life after lung transplantation in Brazil. ■ Supports future clinical monitoring and research on transplant outcomes. ABSTRACT Objective: To translate, cross-culturally adapt, and validate the Lung Transplant Quality of Life questionnaire […]

Highlights ■ This study describes a series of cases in which SARS-CoV-2  infection is associated with profound sensorineural hearing loss. ■ COVID-19 infections can indeed cause sensorineural hearing loss. ■ Seven patients with profound sensorineural hearing loss due to COVID-19 were clinically evaluated and underwent audiological testing. ■ This study highlights that the consequences of COVID-19 extend beyond respiratory symptoms and affect other systems, such as the inner ear. ABSTRACT Objective: To describe a series of cases in which severe […]

Highlights ■ The exercise program reduced the WOMAC score by 50%, VAS score by 53%, and improved isokinetic strength. ■ There were no significant changes in levels of serum COMP, MMPs, or pro-inflammatory cytokines. ■ Biomarker levels did not correlate with clinical improvement outcomes. ■ This exercise program is feasible for knee osteoarthritis management in primary care. ABSTRACT Objective: To evaluate a simplified exercise program for patients with knee osteoarthritis in terms of pain, functionality, muscle strength, and quality of […]

Highlights ■ The return to work rate was 53.7%, with slower and lower reintegration among low-income recipients. ■ Individuals with higher socioeconomic status (Classes A and B) were over twice as likely to return to work compared with lower socioeconomic status. ■ Higher stigma scores were significantly associated with reduced quality of life in Functional Capacity, Mental Health, and Social Functioning domains (p<0.001). ■ Older age (≥51 years), racial disparities, and unemployment before transplantation were strong barriers to occupational reintegration. […]

Highlights ■ Assessing how vascular access devices affect quality of life is essential to effectively manage chemotherapy patients. ■ The translation and validation of the QoLVAD questionnaire demonstrated that the Brazilian Portuguese version can be applied to the Brazilian population. ABSTRACT Background: The use of long-term devices for chemotherapy in neoplastic diseases is very common. The CAVA trial was an extensive study that prospectively evaluated more than 1000 patients undergoing chemotherapy and randomly allocated them to three groups based on […]

Highlights ■ Gestational trophoblastic disease should be followed up at a referral center. ■ Adequate follow-up improves quality of life for affected women. ■ Multidisciplinary monitoring reduces anxiety and depression in women. ABSTRACT Objective: To evaluate the psychological repercussions of gestational trophoblastic disease. Methods: A cross-sectional study including 100 women (50 with gestational trophoblastic disease and 50 without) was conducted between September 2020 and October 2021. Socio-demographic characteristics, quality of life, depression, and anxiety were evaluated and follow-up was performed […]

Highlights ■ Liver transplantation improves health-related quality of life in patients with cirrhosis and high MELD scores. ■ Significant health-related quality of life improvements occur within three months of transplantation. ■ Multidisciplinary care programs enhance post-iver transplantation physical and mental recovery. ■ Sustained health-related quality of life gains highlight the long-term benefits of liver transplantation. ABSTRACT Objective: To assess the effects of liver transplantation on the health-related quality of life of patients with cirrhosis on the waiting list for transplantation. […]

ABSTRACT In Brief Chikungunya fever compromises the functionality and quality of life in the affected individuals, even one year after the acute phase of the disease. Chronically affected people experience direct impairment in performing daily activities, along with a risk of developing other morbidities. Highlights Even after a year, chikungunya fever-affected people experience damage to their physical and mental health. Positive screening for depression risk was 13.5 times more likely in chronically affected. Patients with chronic chikungunya fever had a […]

Highlights Sociodemographic, clinical, and lifestyle factors impact the quality of life of breast cancer survivors. Breast cancer therapy may affect future perspectives and emotional, cognitive, and sexual function. Some aspects of quality of life still require attention from health professionals. ABSTRACT Objective: Patients with cancer often undergo multiple extended treatments that decrease their quality of life. However, the quality of life of women with breast cancer after they undergo treatment remains underexplored in Brazil. Therefore, this study determined sociodemographic, behavioral, […]

ABSTRACT Objective To review the long-term outcomes (functional status and psychological sequelae) of survivors of critical illnesses due to epidemic viral pneumonia before the COVID-19 pandemic and to establish a benchmark for comparison of the COVID-19 long-term outcomes. Methods This systematic review of clinical studies reported the long-term outcomes in adults admitted to intensive care units who were diagnosed with viral epidemic pneumonia. An electronic search was performed using databases: MEDLINE®, Web of Science™, LILACS/IBECS, and EMBASE. Additionally, complementary searches […]