Highlights ■ Remaining obese over time was independently associated with higher odds of depression. ABSTRACT Objective: To evaluate the association between longitudinal self-initiated changes in body mass index patterns and depression in a large sample of adults and older individuals. Methods: Participants included 1,944 adults and older individuals with depressive symptoms at baseline who underwent routine health screening examinations. Depression was defined as Beck Depression Inventory-II scores ≥14. Body mass index, blood pressure, blood samples, alcohol consumption, smoking status, physical […]

Highlights ■ Forty-four percent of mothers of children with autism spectrum disorder have poor sleep quality. ■ Seventy percent did not meet the recommended 7-9 hours of sleep. ■ Demographic, child-related, and clinical data were associated with sleep problems. ABSTRACT Objective: To analyze the factors associated with sleep quality and duration in mothers of children with autism spectrum disorder. Methods: A cross-sectional study was conducted with 595 mothers (37±7yrs) of children and adolescents with autism spectrum disorder (8.1±3.1yrs). The assessed […]

Highlights High fatigue and nutritional risk at discharge improved over one year in cancer survivors. Psychological symptoms, such as anxiety, depression, and posttraumatic stress disorder, remained prevalent for one year. 66% of patients had lasting symptoms or impairments after 12 months of follow-up. Nutritional risk was resolved in the following year. ABSTRACT Objective: Post-COVID symptoms are frequent and can be debilitating, particularly in individuals with cancer. However, their impact on this population remains unclear. This study aimed to prospectively assess […]

Highlights ■ Gestational trophoblastic disease should be followed up at a referral center. ■ Adequate follow-up improves quality of life for affected women. ■ Multidisciplinary monitoring reduces anxiety and depression in women. ABSTRACT Objective: To evaluate the psychological repercussions of gestational trophoblastic disease. Methods: A cross-sectional study including 100 women (50 with gestational trophoblastic disease and 50 without) was conducted between September 2020 and October 2021. Socio-demographic characteristics, quality of life, depression, and anxiety were evaluated and follow-up was performed […]

Highlights ■ Persistently active individuals have strong independent protective factors against depression. ■ BMI (kg/m2) is an independent risk factor for depression. ■ Individuals with depression at follow-up were older than those without depression. ■ Perceived stress is a strong independent risk factor for depression. ABSTRACT Objective: To evaluate the association between changes in physical activity and depression in 1,950 Brazilians. Methods: This follow-up study included 1,950 Brazilians, aged ≥18 years, of both sexes, who participated in a health screening […]

Highlights Levels of lower urinary tract symptoms increased the risk of depression. Erectile dysfunction, alcohol consumption, and body mass index were associated with an increased likelihood of depression. ABSTRACT Objective: This study aimed to investigate the relationship between depression and erectile dysfunction while controlling for sociodemographic, physical health, psychological, and lifestyle factors. Additionally, it aimed to compare erectile dysfunction with other clinical, laboratory, and behavioral variables among individuals with depression in the same population. Methods: We included 21,139 men (≥40 […]

Highlights ■ Continuous exosomatic electrodermal activity was associated with higher skin conductance levels in patients with hyperhidrosis. ■ Palmoplantar sweating was significantly higher in the hyperhidrosis group than in the control group (p<0.01). ■ Electrodermal activity is an effective and simple method for objectively quantifying sweating in patients with hyperhidrosis. ABSTRACT Objective: To objectively evaluate sweat intensity in patients with primary hyperhidrosis by measuring electrodermal activity using a continuous exosomatic technique without external stimuli. Methods: This prospective and transversal study […]

Highlights Chronic pain is directly associated with depressive symptoms and frailty. Chronic pain is not directly associated with functional disability. Depression and frailty are both directly associated with functional disabilities. Frailty mediates the association between chronic pain and functional disability. ABSTRACT Objective: To evaluate the direct and indirect effects of chronic pain, depressive symptoms, frailty components, and functional disability through a pathway analysis approach in a sample of community-dwelling older adults. Methods: Data of 419 participants were cross-sectionally evaluated for […]

Highlights Perinatal L-NAME treatment decreased anxiety- and depression-like behaviors in adult mice. Perinatal L-NAME treatment did not promote changes in locomotor activity in adult mice. Perinatal L-NAME treatment did not alter pain perception ABSTRACT Objective: We hypothesized that perinatal manipulations of the nitrergic system would affect adult animal behaviors. Methods: We tested this hypothesis by perinatally administering N(G)-Nitro-L-arginine methyl ester (L-NAME), a non-specific antagonist of nitric oxide synthase for 15 days and assessed anxiety- and depression-like behaviors in adult mice. […]

ABSTRACT Introduction Gratitude has several implications. Over time, a logical relationship has been established between gratitude and well-being. In addition, researchers aimed to establish associations between gratitude and other factors of positive feelings using scientific methods. We conducted a systematic review and meta-analysis of interventions to develop gratitude and its benefits to human beings. Objective This study aimed to evaluate and quantify the available scientific evidence on interventions to acquire knowledge on gratitude as a quantifiable causal factor of benefit […]