Highlights Gradient Boosting Machine and Random Forest models were built for prediction of mortality at cardiac intensive care units. A total of 9,761 intensive care unit stays of patients admitted under a Cardiac Surgery and Cardiac Medical services were studied. The AUROC and AUPRC values were significantly superior to seven conventional systems compared. The machine learning models’ calibration curves were substantially closer to the ideal line. ABSTRACT Objective: Logistic Regression has been used traditionally for the development of most predictor […]

Highlights Probable sarcopenia plus malnutrition was significantly associated with unplanned readmission. Overlap of probable sarcopenia and malnutrition was an independent risk factor for readmission. Certification of whether the patient is malnourished and/or sarcopenic preoperatively is necessary. SARC-F and subjective global assessment can effectively and easily assess sarcopenia and malnutrition at admission. ABSTRACT Objective: To assess the 30-day unplanned readmission rate and its association with overlapping probable sarcopenia and malnutrition after major oncological surgery. Methods: A prospective bicentric observational cohort study […]

Highlights Simulation-based training is a valuable strategy for achieving positive changes in obstetric practice. The rate of vaginal births increased after the intervention. The findings underscore the potential advantages of incorporating simulation training into quality improvement initiatives. Higher training adoption rates correlated with substantial and sustained enhancements in vaginal birth rates. ABSTRACT Objective: This study aimed to analyze the relationship between the participation of professionals in simulation-based training and an increase in the rate of vaginal deliveries. Methods: This retrospective […]

Highlights Incorporation of secukinumab and ustekinumab was economically feasible. These drugs are options for those who do not respond to or have contraindications to etanercept. ABSTRACT Objective: Therefore, this study aimed to evaluate the impact of secukinumab and ustekinumab against moderate-to-severe plaque psoriasis in a Brazilian pediatric population with access to public healthcare. Methods: A survey of immunobiological treatments registered for use against pediatric psoriasis at the National Health Surveillance Agency was conducted. These treatments were compared to the list […]

Highlights One-step synthesis provides affordable, stable, and biocompatible nanoparticles. PEG-coated gold nanoparticles exhibited very low cytotoxicity effects. This in vivo study did not reveal hematopoietic, renal, or hepatic alterations. The histopathological analysis did not present any tissue or cellular damage. ABSTRACT Objective: To evaluate the in vitro and in vivo toxicities of polyethylene glycol-coated gold nanoparticles synthesized using a one-step process. Methods: Gold nanoparticles were prepared via a co-precipitation method using polyethylene glycol, and the synthesis product was characterized. For […]