31/Oct/2024
Face mask use and viral load in patients with mild symptoms of COVID-19
DOI: 10.31744/einstein_journal/2024AO0495
Highlights ■ Probability of infection with a high SARS-CoV-2 viral load depends on mask-wearing habits. ■ The higher probability of infection with high viral load occurs for individuals that don’t use mask regularly [47.3%–79.8%]. ■ For individuals who use masks regularly, the probability is 38.6%–52.1%. ABSTRACT Objective: Previous studies indicated that face masks reduce the probability of infection by SARSCoV- 2 but did not examine the relationship between SARS-CoV-2 viral load and mask usage. This study analyzed this relationship. Methods: […]
Keywords: Communicable diseases; Coronavirus disease; COVID-19; Infectious; Masks; N95 respirators; Respiratory protective devices; SARS-CoV-2; Viral load
23/May/2023
Suppression of HIV in the first 12 months of antiretroviral therapy: a comparative analysis of dolutegravir- and efavirenz-based regimens
DOI: 10.31744/einstein_journal/2023AO0156
Highlights Viral suppression improved after introducing a dolutegravir-based regimen. HIV viral loads <50 copies/mL were lower than expected (<90%). Higher viral suppression was found when antiretroviral therapy adherence/alterations were controlled (per-protocol analysis). Some baseline characteristics can influence the effectiveness of first-line antiretroviral therapy. ABSTRACT Objective To compare viral suppression in treatment-naïve adults starting antiretroviral therapy with dolutegravir (50mg)- and efavirenz (600mg)-based regimens. Methods We analyzed secondary data from Brazilian health information systems of people living with human immunodeficiency virus who […]
Keywords: Anti-HIV agents; Antiretroviral therapy, highly active; Dolutegravir; Drug therapy, combination; Efavirenz; Effectiveness; HIV-1; Sustained virologic response; Viral load