13/Aug/2025
Atrophic hypothyroidism associated with thyrotropin receptor antibodies
DOI: 10.31744/einstein_journal/2025RC1400
ABSTRACT Hypothyroidism is most frequently caused by Hashimoto’s thyroiditis. While thyrotropin receptor antibodies are well-known in Graves’ disease-induced hyperthyroidism, their role in hypothyroidism is emerging. We report the case of a 37-year-old woman with facial and periorbital edema, weight gain, and hoarseness suggestive of hypothyroidism. Elevated thyroid stimulating hormone (TSH; 131mIU/L) and decreased free thyroxine (0.2ng/dL, 2.6pmol/L) levels confirmed this diagnosis. Laboratory findings showed dyslipidemia, impaired renal function, elevated creatine phosphokinase levels, and anemia. Despite negative results for thyroid peroxidase […]
Keywords: Autoantibodies; Hashimoto disease; Hypothyroidism; Long-acting thyroid stimulator; Pregnancy; Receptors, thyrotropin; Thyroiditis; Thyroiditis, autoimmune; Thyrotropin
22/Apr/2025
Prevalence of autoimmune diseases in patients with type 1 diabetes: a scoping review
DOI: 10.31744/einstein_journal/2025RW1222
ABSTRACT Objective To evaluate the prevalence of autoimmune diseases in patients with type 1 diabetes mellitus. Methods This scoping review was conducted following the Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) tool to ensure methodological rigor. We systematically searched PubMed, Embase, Scopus, Lilacs, and Web of Science databases to identify relevant literature published between 2018 and 2023. Results Twenty-four studies were included, mostly single-center studies from six continents, […]
Keywords: Addison disease; Autoimmune diseases; Celiac disease; Diabetes mellitus, type 1; Thyroiditis, autoimmune