23/Jun/2023
RT-qPCR-based pool testing for the diagnosis of COVID-19
DOI: 10.31744/einstein_journal/2023AE0115
Highlights Pool testing is simultaneously performed on multiple samples to efficiently and cost-effectively detect COVID-19. Pool testing can optimize resource utilization and expand diagnostic access, and is a viable alternative for developing countries with limited access to testing. To optimize resources, the pool size was determined by estimating COVID-19 prevalence in the study population. ABSTRACT This study proposes a strategy for large-scale testing among a large number of people for the early diagnosis of COVID-19 to elucidate the epidemiological situation. […]
Keywords: Coronavirus infections; COVID-19; Pandemics; Reverse transcriptase polymerase chain reaction; SARS-CoV-2
18/Jul/2022
Effect of lateral decubitus acquisition in accuracy and lung severity estimation of chest computed tomography in children with suspected COVID-19
einstein (São Paulo). 18/Jul/2022;20:eAO0061.
View Article18/Jul/2022
Effect of lateral decubitus acquisition in accuracy and lung severity estimation of chest computed tomography in children with suspected COVID-19
DOI: 10.31744/einstein_journal/2022AO0061
ABSTRACT Objective To compare inter-rater reliability, diagnostic accuracy, and extension of pulmonary involvement in children with suspected COVID-19 submitted to supine or supine and lateral decubitus computed tomography imaging. Methods Retrospective study carried out between March 2020 and March 2021 with patients submitted to reverse transcription-polymerase chain reaction testing and chest computed tomography. Patients were divided into two groups: supine or supine and lateral decubitus imaging. Standardized reporting systems of computed tomographic findings in COVID-19 and chest computed tomography score […]
Keywords: Child; Coronavirus infections; COVID-19; Multidetector computed tomography; Reverse transcriptase polymerase chain reaction; Tomography, x-ray computed
26/Oct/2021
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR
DOI: 10.31744/einstein_journal/2021AO6363
ABSTRACT Objective To evaluate the role of chest computed tomography in patients with COVID-19 who presented initial negative result in reverse transcriptase-polymerase chain reaction (RT-PCR). Methods A single-center, retrospective study that evaluated 39 patients with negative RT-PCR for COVID-19, who underwent chest computed tomography and had a final clinical or serological diagnosis of COVID-19. The visual tomographic classification was evaluated according to the Consensus of the Radiological Society of North America and software developed with artificial intelligence for automatic detection […]
Keywords: Coronavirus infections; Reverse transcriptase polymerase chain reaction; Tomography, x-ray computed