2 results
17/Oct/2024
17/Oct/2024
DOI: 10.31744/einstein_journal/2024AO0821
Highlights Tofacitinib use did not result in meaningful changes in hematological parameters. Tofacitinib use did not lead to clinically meaningful changes in liver enzymes. ABSTRACT Objective: Tofacitinib, an oral Janus kinase inhibitor, has been tested against a placebo in 289 patients with COVID-19 pneumonia. We analyzed the data from the tofacitinib- and placebotreated patient cohorts to evaluate the laboratory profiles between baseline and day 7. Methods: We performed post hoc analyses on the following laboratory tests over time during the […]
Keywords: Alanine transaminase; Aspartate aminotransferases; Coronavirus infections; COVID-19; Janus kinase inhibitors; Lab results; Platelet count; Pneumonia; Tofacitinib
20/Dec/2019
DOI: 10.31744/einstein_journal/2020RC5111
ABSTRACT Situs inversus totalis is a rare recessive autosomal congenital abnormality in which the mediastinal and abdominal organs are in a mirrored position when compared to the usual topography. The literature reports some cases of situs inversus totalis and concomitant conditions: spinal abnormalities, cardiac malformations and hematological diseases, such as idiopathic thrombocytopenic purpura, which is an autoimmune disease that causes thrombocytopenia due to platelet destruction or suppression of its production. This article aimed to report the coexistence of situs inversus […]
Keywords: Exome; Hematologic diseases; Platelet count; Purpura, thrombocytopenic; Situs inversus