Highlights ■ In this study, mice were exposed to music at the intrauterine stage. ■ Music exposure before aversive memory formation enhances neuroplasticity, aiding in extinction. ■ The recall test showed that music exposure had sustained beneficial long-term effects. ABSTRACT Objective: This study aimed to analyze the influence of Mozart’s Sonata K.448 on contextual memory extinction in male mice. Methods: Male mice were divided into three groups (G1-Mozart, G2-Ambience, G3-Control). Throughout the project, only the first group was exposed to […]

OBJECTIVE: The hippocampus has an important role in the acquisition and recall of aversive memories. The objective of this study was to investigate the relationship among hippocampal rhythms. METHODS: Microeletrodes arrays were implanted in the hippocampus of Wistar rats. The animals were trained and tested in a contextual fear conditioning task. The training consisted in applying shocks in the legs. The memory test was performed 1 day (recent memory) or 18 days (remote memory) after training. We proposed a measure […]