INTRODUCTION Despite medical advances and numerous efforts to mitigate cognitive decline, aging remains a universal process affecting all individuals.()Cognitive decline complexity in the older population results from the interplay of various aging-related factors, including cellular senescence, epigenetic modifications, and metabolic dysfunction. Brain aging phenotypes, such as vascular dysfunction, inflammation, and lipid dysregulation, further interact with central nervous system processes, leading to morphological, cognitive, and neuropathological changes, ultimately contributing to neurodegenerative diseases.() Dementia, characterized by severe cognitive decline that interferes with […]

ABSTRACT Objective To evaluate the epidemiological profile of patients seen at a dementia outpatient clinic. Methods A retrospective study conducted by medical record review searching data on sex, race, age, schooling level, and diagnosis of patients seen from 2008 to 2015. Results A total of 760 patients were studied, with a predominance of female (61.3%; p