Highlights Fatality due to COVID-19 does not alter the time under oncological palliative care. The retrospective design of this pioneering study allows causal inference. Access to oncological palliative care frequently approaches terminality of life. ABSTRACT Objective: This study aimed at investigating the extent to which COVID-19-induced fatalities affect the duration of palliative care among patients with advanced cancer. Methods: A retrospective cohort study was conducted at the Palliative Care Unit of the Brazilian Instituto Nacional de Câncer in Rio de […]

ABSTRACT In Brief Chikungunya fever compromises the functionality and quality of life in the affected individuals, even one year after the acute phase of the disease. Chronically affected people experience direct impairment in performing daily activities, along with a risk of developing other morbidities. Highlights Even after a year, chikungunya fever-affected people experience damage to their physical and mental health. Positive screening for depression risk was 13.5 times more likely in chronically affected. Patients with chronic chikungunya fever had a […]

ABSTRACT In Brief Queiroz et al. showed that the application of cluster methodology for classifying gastric cancer is suitable and efficient within a Brazilian cohort, which is known for its population heterogeneity. The study highlighted the potential utilization of this method within public health services due to its low-cost, presenting a viable means to improve the diagnosis and prognosis of gastric cancer. Highlights Our Brazilian cohort with gastric cancer has a distinct distribution between mutated and normal p53. New genetic […]

ABSTRACT In Brief Angiography of the superior rectal artery showed that its branches were divided into four main branches (two left and two right) in 46.8%; the second most frequent variation was one right and two left branches in 26.6%, followed by two branches to the right and one to the left in 20%; the most uncommon variations were one to the right and one to the left without further subdivision in 6.6%. Highlights The superior rectal artery, when it […]

Highlights Klotho controls cellular pathways and is a key factor in senescence and longevity. FGF-23 regulates phosphorus and vitamin D metabolism in a Klotho-dependent manner. Bone formation in Klotho-deficient mice decreased similar to that in aged humans. Renal function and lumbar spine bone mineral density were related to Klotho and FGF-23, respectively. ABSTRACT Objective: To investigating the relationship between α-Klotho and FGF-23 with bone biochemical markers and bone density findings in extremely aged individuals. Methods: A total of 55 individuals […]

Highlights From the One Health approach, empathy represents the initial movement towards achieving planet harmony. The more emotions we attribute to animals, the more we develop pro-conservation behaviors. AES-Brazil may serve as a tool for reflection and monitoring interventions in human-animal relationships. ABSTRACT Objective: To design and validate a Brazilian version of the Animal Empathy Scale, based on the existing Portuguese version. Methods: Content validity assessment was performed by expert judges, and the adapted scale was administered to a sample […]

Highlights Small-litter promotes greater body weight gain, adiposity, and metabolic abnormalities in adulthood. Small-litter -adult obese rats showed augmented hypothalamic expression of GLP1-R and Lep-R. Swimming training throughout life avoids obesity and metabolic disorders in small-litter-adult rats. Regular exercise can normalize GLP1-R and Lep-R hypothalamic expressions in small-litter-adult rats. ABSTRACT Objective: Glucagon-like peptide-1 (GLP1) and leptin (Lep) are afferent signals that regulate energy metabolism. Lactational hypernutrition results in hyperphagia and adiposity in adult life, and these events can be prevented […]

Highlights Excess moisture can lead to maceration and contribute to skin breakdown. Superficial pressure ulcers were the most common and can be easily prevented. Healthcare professionals should be aware of PU risk factors, evaluate skin daily, and offer prevention. ABSTRACT Objective: To estimate the point prevalence of and risk factors associated with the development of pressure ulcers at a university hospital in Brazil. Methods: This study was conducted on 196 participants using a structured questionnaire, physical examination of the skin, […]

Highlights A  single-center study evaluated the prevalence and risk factors for Burnout syndrome in intensive care unit teams. The study revealed a high prevalence of Burnout syndrome in at least one dimension. Factors such as profession and having two or more jobs were associated with severe burnout symptoms. The study highlighted the need for interventions and support to address burnout among intensive care unit teams. ABSTRACT Objective: To evaluate the prevalence of burnout among the intensive care unit team of […]

Highlights Only 20% of the medical residency programs have laparoscopic teaching. Preceptors of the residency programs have advanced experience. Most programs have no plan to set up a training center. Resideny programs are concentrated in the Southeast region and in capitals. ABSTRACT Objective: To characterize laparoscopy teaching in Medical Residency Programs in Gynecology and Obstetrics in Brazil, and to evaluate preceptors’ characteristics in laparoscopy programs and map laparoscopic training practice scenarios. Methods: This descriptive cross-sectional study evaluated questionnaire responses from […]