Category: Robotic Technology in Thoracic Diseases Introduction: Although usually of an indolent nature, thymoma recurrence rates vary between 15% and 50%.() While surgery remains the cornerstone of treatment, advanced or recurrent thymomas present significant challenges due to their invasive nature and propensity for local recurrence. Hyperthermic intrathoracic chemotherapy (HITHOC) has emerged as a promising adjunctive therapy to address these challenges.(,) This case report presents the utility and outcomes of HITHOC associated with robotic-assisted thoracic surgery (RATS) in the management of […]

Category: Robotic Technology in Thoracic Diseases Introduction: Robotic-assisted thoracic surgery (RATS) is well-established for the treatment of mediastinal tumors. Oncological results are comparable to invasive techniques, albeit providing fewer complications and less postoperative pain.(,) We present our initial experience with the subxiphoid technique. Methods: This retrospective case series includes patients submitted to RATS subxiphoid thymectomy. Demographic, perioperative, and postoperative data were gathered, analyzed, and reported with descriptive statistics. Results: Case 1: A 48-year-old woman, ex-smoker, with a history of colon […]

Category: Robotic Technology in Thoracic Diseases Introduction: Colorectal cancer (CRC) is the leading cause of cancer death worldwide.() It is estimated that about 50% of patients with CRC develop metastasis during follow-up, most commonly in the liver followed by the lung. Lung metastasis is seen in approximately 10 – 15% of patients diagnosed with CRC.(,) Pulmonary metastasectomy is the treatment with the best survival rate.() Due to the high incidence of lung recurrence, in approximately 50% of cases, parenchyma-sparing lung […]

Category: Robotic Technology in Thoracic Diseases Introduction: Recent two randomized studies have demonstrated that for lung cancers peripherally and smaller <2cm, segmentectomy accompanied by intraoperative lymph node assessment is as effective as lobectomy in terms of overall survival.() The video presents a comprehensive guide to performing a right robotic segmentectomy, specifically of segments 9 of the lung.() This includes a thorough hilar and mediastinal nodal dissection. Additionally, the video showcases the application of Indocyanine Green (ICG) to accurately identify the […]

Category: Thoracic Oncology Introduction: Genomic mutational profiling, obtained through next-generation sequencing (NGS) plays a pivotal role in assisting clinicians in therapeutic decision- making in patients with non-small cell cancer (NSCLC).(,) However, these techniques require high quality and sufficient quantity of material to produce reliable results.(,) Our study proposes the use of tissue scraping from histological and cytological slides as an alternative method for obtaining genomic DNA (gDNA) of better quality and quantity, and also an optimized extraction protocol from paraffin […]

Category: Thoracic Oncology Introduction: Despite the proven survival benefits of adjuvant systemic therapy (AT) in resected non-small-cell lung cancer (NSCLC), its underutilization remains a concern.(–) Objecitve: This study aims to explore the extent to which socioeconomic disparities influence AT underutilization. Methods: Data from the Brazilian Registry of Lung Cancer (2009-2023), was queried for patients with complete surgical resected stage IB-III and stratified based on AT delivery. Demographic, clinical, and pathological variables were evaluated. Logistic regression model was performed. The model’s […]

Category: Thoracic Oncology Introduction: Hyperthermic intrathoracic chemotherapy has been used as an adjuvant treatment after surgical resection of patients diagnosed with disseminated pleural neoplastic disease. The most frequent uses refer to malignant pleural mesothelioma and thymic tumors.(,) Objective: This study aims to describe our initial experience implementing this method of hyperthermic chemotherapy used after cytoreductive surgery. Methods: This is a retrospective study with a series of cases of patients who underwent pleural decortication followed by HITOC. We collected demographic and […]

Category: Thoracic Oncology Introduction: Primary tracheal tumors have a prevalence around 0.2% of the entire respiratory system.() Two-thirds of tracheal tumors are malignant, of which 75% are squamous cell carcinoma and 15% are adenoid cystic carcinoma. Due to the low incidence, we chose to report the case of a patient with adenoid cystic carcinoma approached via videothoracoscopy and sternotomy with incomplete resection of the lesion (R1) with clinical and radiological control of the disease following adjuvant therapy.() Case video Summary: […]

Category: Thoracic Oncology Introduction: Bronchogenic tumors, predominantly non-small cell type (NSCLC), are a global health concern, with adenocarcinomas, their most common subtype, being most often diagnosed at advanced stages, making it essential to develop effective therapeutic strategies, especially for patients with NSCLC who do not express the PD-L1 (Programmed Death-Ligand 1) protein. Two pivotal studies, Keynote-189() and Keynote-407,() presented their combined results in 2023, after a 5-year follow-up,() concluding that the combination of Pembrolizumab and chemotherapy demonstrated substantial improvements in […]

Category: Thoracic Oncology Introduction: The prognostic evaluation of early-stage non-small cell lung cancer (NSCLC) remains critical for optimizing treatment strategies and improving patient outcomes.(–) Objective: This study aims to delineate the pivotal predictors affecting survival rates among early-stage NSCLC patients, leveraging data from the Brazilian Lung Cancer Registry. Methods: This study retrospectively analyzed data from the Brazilian Lung Cancer Registry, encompassing 2,045 patients who underwent surgical treatment for lung cancer across 14 institutions in five Brazilian states. The registry is […]