2 results
23/Nov/2023
DOI: 10.31744/einstein_journal/2023RC0621
ABSTRACT Molecular imaging markers can be used to differentiate between infection and aseptic inflammation, determine the severity of infection, and monitor treatment responses. One of these markers is ubiquicidin(29-41) (UBI), a cationic peptide fragment that binds to the bacterial membrane wall and is labeled with gallium-68 (68Ga), a positron emitter radioisotope. The use of UBI in positron emission tomography (PET)/computed tomography (CT) for improved detection of lesions has been receiving considerable attention recently. Herein, we report the first case of […]
Keywords: Antimicrobial peptides; Bacterial infections; Osteomyelitis; Positron emission tomography computed tomography; Radiopharmaceuticals; Staphylococcal infections; Staphylococcus aureus
08/Nov/2019
DOI: 10.31744/einstein_journal/2020GS4816
ABSTRACT Objective To expose the current situation of the Brazilian Nuclear Medicine in relation to innovation, taking into account the Intellectual Property protection and the particularities of this field. Methods The number and the origin of patents filings from Brazil, United States and European Patent Convention countries were retrospectively compared in a 20-year period. Results The number of accumulated patents filings of conventional pharmaceuticals was ten times higher compared to the radiopharmaceuticals in the three regions studied. Conclusion The largest […]
Keywords: Innovation; Intellectual Property; Nuclear medicine; Patent; Radiopharmaceuticals