29/May/2025
Mucocutaneous disease: a child with extrapulmonary manifestation of mycoplasma infection
DOI: 10.31744/einstein_journal/2025RC1138
ABSTRACT Mycoplasma-induced rash and mucositis is a distinctive subset of reactive infectious mucocutaneous eruption identified in 2015 to differentiate it from other mucocutaneous disorders such as Stevens-Johnson syndrome, erythema multiforme major, and toxic epidermal necrolysis. Although its pathophysiology is not completely understood, Mycoplasma-induced rash and mucositis is characterized by polyclonal B cell proliferation, production of antibodies against Mycoplasma pneumoniae, subsequent immune complex deposition, and keratinocyte apoptosis. Clinical manifestations include scattered cutaneous lesions and severe mucositis, which predominantly affect children and […]
Keywords: Child; Diagnosis, differential; Erythema multiforme; Exantema; Mucositis; Mycoplasma; Mycoplasma infections; Mycoplasma pneumoniae
14/Jun/2022
Report of a clinical and laboratory management of cell therapy for knee cartilage in the face of mycoplasma contamination
DOI: 10.31744/einstein_journal/2022RC6918
ABSTRACT To describe a case of autologous chondrocyte implantation after cell culture contamination by Mycoplasma pneumoniae and the measures taken to successfully complete cell therapy in a patient with focal chondral lesion. A 45-year-old male patient, complaining of chronic pain on the knee and no history of trauma. He had a chondral lesion in the trochlear region of the femur and clinical tests compatible with pain in the anterior compartment of the knee. Conservative treatment failed to alleviate symptoms. Surgical […]
Keywords: Cartilage; Cell culture techniques; Cell- and tissue-based therapy; Chondrocytes; Knee; Mycoplasma