Highlights ■ In-house 68Ga radiopharmaceutical synthesis under GMP in a tertiary hospital radiopharmacy. ■ Over 7,500 patients underwent imaging with [68Ga]Ga-  DOTATATE and [68Ga]Ga-PSMA-11. ■ This is the first radiopharmacy in Brazil to introduce [68Ga] Ga-DOTA-UBI, and [68Ga]Ga-FAPi-46. ABSTRACT In this study, we report the implementation of in-house synthesis of gallium-68 (68Ga)-labeled radiopharmaceuticals for positron emission tomography (PET) at a tertiary hospital radiopharmacy. [68Ga]Ga-DOTATATE and [68Ga]Ga-PSMA-11 were introduced into clinical practice in January 2014 and October 2015, respectively, following the […]