Publications in: “00/03/2019”

Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation

Cytomegalovirus infection and its reactivation is frequent after solid organs and hematopoietic stem cell transplantation, and this infection can cause significant impact on transplantation outcomes. In mouse experimental models and in hematopoietic stem cells, an infusion in the presence of strain-specific anti-cytomegolovirus, was protective. There is the need for antibodies specific for the strain that was presented. Commercial immunoglobulin infusions were tried in bone marrow transplantation and solid organ transplantation as prophylactic or therapeutic measures against cytomegalovirus, but trials did […]

We need to develop new antibiotics

Progressing of antibiotic resistance in bacteria erodes our therapeutic resources. Some infections are caused by bacteria that have only one or no therapeutic options. New antibacterial agents should be developed, but economic considerations conspire against investing in this market. Antibiotics are used, at most, two weeks for serious infections, and there is a tendency of lesser time use. Infection control wants exactly that: to control new antibiotic use to delay resistance, so the market for those new drugs is restricted. […]

HIV viral load and transmissibility of HIV infection: undetectable means non transmissible

Many evidences exist on undetectable HIV viral load – which means less than 200 genomic copies/ml signifies that a patient will not transmit infection to other person. This small. but powerful review article, insists that all persons with HIV should adhere to treatment and have their viral load controlled, as a measure of public health. If such measurable is done, as widely as possible, we can stop HIV epidemic. Eisinger RW, Dieffenbach CW, Fauci AS. HIV viral load and transmissibility […]