Highlights Autoimmune hepatitis and systemic lupus erythematosus share several clinical features. Anti-P ribosomal antibody is a biomarker for systemic lupus erythematosus. The association between anti-P ribosomal antibody and autoimmune hepatitis has shown conflicting results. Our results showed no association between anti-P ribosomal antibody and autoimmune hepatitis. ABSTRACT Objective: Published studies have shown associations between anti-ribosomal P (anti-P) antibody and systemic lupus erythematosus with hepatic manifestations. This has been reported also in autoimmune hepatitis. However, the consistency of the latter association […]

Highlights Face masks are associated with ear discomfort. Face masks increase the pulse rate. Face masks reduce arterial blood oxygen saturation. Face masks are less tolerated by young men. ABSTRACT Objective: The World Health Organization and Centers for Disease Control and Prevention recommend the use of face masks in public. This study aimed to evaluate the effects of face masks on pulse rate and partial blood oxygen saturation in patients without cardiorespiratory disorders. Methods: A total of 150 volunteers of […]

Highlights Inhibition of endocannabinoid receptors and TNF-α led to an increase in HLA-DR, PD-L1, and PD-L2 levels in stem cells from human exfoliated deciduous teeth. This study shows the interaction between mesenchymal stromal cells and the immune and endocannabinoid systems. ABSTRACT Objective To verify the involvement of the endocannabinoid system in the immunomodulatory profile of stem cells from human exfoliated deciduous teeth, in the presence or absence of TNF-α, and agonist and antagonists of CB1 and CB2. Methods Stem cells […]

Highlights Once complete hepatocellular carcinoma necrosis is achieved, the diameter of the hepatocellular carcinoma decreases significantly, regardless of its initial size. Hepatocellular carcinoma >3cm showed greater reduction and longer time to recurrence. Hepatocellular carcinoma ≤3cm exhibited a shorter time to relapse. Recurrence rates were similar, as long as complete response was achieved. ABSTRACT Objective: To describe the radiological characteristics of hepatocellular carcinoma (HCC) lesions that achieved a complete response following drug-eluting bead transarterial chemoembolization (DEB-TACE) preceding liver transplantation. Methods: This […]

Highlights The predominance of neutrophils was observed in an acute model of gout in mice, where neutrophils were mobilized and gradually replaced by monocytes/macrophages, with attenuation of the influence of leukocyte infiltration in the synovial fluid. Mobilization promotes analgesia and modulates the inflammatory process due to reduced edema and subtle attenuation of cell migration. At the inflammatory peak in a gouty arthritis model, manual therapy and passive joint mobilization decrease nociception and edema in functional and inflammatory parameters. ABSTRACT Objective: […]

Highlights First study to investigate the rs10835638 variant in Brazilian women with endometriosis. The homozygous TT genotype was very rare among Brazilian women. G۪۪enotype frequencies did not differ between endometriosis and Control Groups. The T allele was more common in minimal/mild endometriosis subgroups than in the Control Group. ABSTRACT Objective: The follicle-stimulating hormone subunit beta gene rs10835638 variant (c.-211G>T) may have detrimental effects on fertility and protective effects against endometriosis. A casecontrol analysis was performed, aiming to investigate the possible […]

Highlights Sanitary restriction measures had a strong impact on usual performance indicators from a selected group of private hospitals in Brazil. Pregnancies and deliveries continued to constitute an important proportion of hospital admissions because they did not depend on external restrictions. Hospital costs increased due to increased utilization of more expensive Personal Protection Equipment (due to lack of availability or much higher demand). ABSTRACT Objective: To analyze the operational and/or financial impacts of regulatory measures implemented by the National Agency […]

Highlights Only 5.5% of Brazilian soccer players surveyed completed higher education. Of these 179 athletes, 67% completed high school. T۪۪he most educated were goalkeepers and defenders at 37% (66/179). Physical education for sports is different from educating the mind in terms of brain plasticity. ABSTRACT Objective: As the soccer culture in Brazil is more popular than schooling, this study reflected on the formal education levels of soccer (football) players through descriptive and quantitative analyses. Methods: We evaluated 179 national soccer […]

Highlights We were unable to prove an association between the use of androgen deprivation therapy and a reduction in factors associated with worse clinical outcomes. Most of the data presented show a tendency to favor the outcomes of patients who do not undergo androgen deprivation therapy, which can be explained by the fact that, in general, their clinical conditions are better and their performance status scores are lower than those of patients who undergo androgen deprivation therapy. ABSTRACT Objective: To […]

Highlights The relative medians of CD3+, CD4+, and CD8+ T cells were significantly higher in women than in men in a healthy indigenous population. Demographic and ethnic diversity of the Brazilian population can be associated with quantitative modifications in the immunologic cells of healthy individuals. Objective: The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development. In Brazil, indigenous people are vulnerable to infections, and few […]