24/jun/2024
Is the colposcopic lesion size a predictor of high-grade lesions in young patients?
DOI: 10.31744/einstein_journal/2024AO0462
Highlights The size of colposcopic lesions appears to be directly related to lesion severity. The size of the lesion is directly related to the severity of the histopathological findings in patients ≥25 years old. The size of the lesion is directly related to the severity of the cytopathological findings in patients aged ≤24 years. ABSTRACT Objective: This study aimed to evaluate whether severity changes with colposcopic lesion size, regardless of age. Methods: This retrospective comparative study reviewed the records of […]
Palavras-chave: Age factor; Colposcopia; Injury Severity Score; Size perception; Squamous intraepithelial lesions of the cervix
24/jun/2024
Multidrug stewardship and adherence to guidelines in >200,000 direct-to-consumer Telemedicine encounters
DOI: 10.31744/einstein_journal/2024AO0707
Highlights Up to 75% of COVID-19 telemedicine patients receive unnecessary drugs; this highlights the need for research. This study assessed the effect of guideline training and feedback on 200,000 telemedicine visits in Brazil. Under 2% of patients with COVID-19 received non-guideline recommended antimicrobials, reflecting high adherence rates. Targeted interventions significantly enhance guideline compliance for safer telemedicine prescriptions. ABSTRACT Objective: The quality of care and safety for Telemedicine-discharged patients with suspected respiratory infections are closely related to low rates of prescriptions […]
Palavras-chave: Doenças transmissíveis; Infecções por coronavírus; COVID-19; Prescrição de medicamentos; Fidelidade a diretrizes; Alta do paciente; Prescrições; Quality Indicators, Health Care; Encaminhamento e consulta; Infecções respiratórias; Telemedicina
14/jun/2024
Adherence to social distancing measures in southern Brazil, 2020/2021: a cross-sectional study
DOI: 10.31744/einstein_journal/2024AO0223
Highlights Approximately one in five respondents adhered to measures of social distancing. Adherence to social distancing was more prevalent in women, older adults with low educational levels, and those affected by multiple chronic diseases. Less than 5% of the population left home normally, whereas the vast majority only went out to carry out essential activities. ABSTRACT Objective: We aimed to analyze the frequency of adherence to social distancing and individual protection measures of adult and older populations in two cities […]
Palavras-chave: Comportamento; Infecções por coronavírus; COVID-19; Pandemics; Physical distancing; Vigilância em saúde pública
06/jun/2024
Effect of transcranial direct current stimulation in the initial weeks post-stroke: a pilot randomized study
DOI: 10.31744/einstein_journal/2024AO0450
Highlights Differences ≥9 points in Fugl–Meyer Assessment scores: sham>active. Connectivity measures: active>sham. ABSTRACT Objective: This study aimed at assessing the alterations in upper limb motor impairment and connectivity between motor areas following the post-stroke delivery of cathodal transcranial direct current stimulation sessions. Methods: Modifications in the Fugl-Meyer Assessment scores, connectivity between the primary motor cortex of the unaffected and affected hemispheres, and between the primary motor and premotor cortices of the unaffected hemisphere were compared prior to and following six […]
Palavras-chave: Connectome; Imagem por ressonância magnética; Motor cortex; Neurological rehabilitation; Acidente cerebral vascular; Transcranial direct current stimulation
06/jun/2024
Prognostic value of programmed cell death ligand 1 (PD-L1) expression in patients with stage III non-small cell lung cancer under different treatment types: a retrospective study
einstein (São Paulo). 06/jun/2024;22:eAO0575.
Ver Artigo06/jun/2024
Prognostic value of programmed cell death ligand 1 (PD-L1) expression in patients with stage III non-small cell lung cancer under different treatment types: a retrospective study
DOI: 10.31744/einstein_journal/2024AO0575
Highlights PD-L1 expression by immunohistochemistry is positive in more than half on stage III non-small lung cancer. PD-L1 expression by immunohistochemistry had no relationship with clinical characteristics. PD-L1 expression by immunohistochemistry is not related to progression-free or overall survival in patients treated with chemoradiotherapy with or without surgery. ABSTRACT Objective: Currently programmed cell death protein 1 (PD-1) inhibitors in combination with other therapies are being evaluated to determine their efficacy in cancer treatment. However, the effect of PD-ligand (L) 1 […]
Palavras-chave: Adenocarcinoma; Carcinoma, non-small-cell lung cancer; Neoplasias do pulmão; Programmed cell death 1 receptor
20/maio/2024
Factors underlying the high occupational risk of healthcare personnel for COVID-19 infection
DOI: 10.31744/einstein_journal/2024AO0433
Highlights COVID-19 infection among healthcare personnel has impacted the workforce in hospitals. Knowledge of the risk factors for COVID-19 infection is important for disease prevention measures. Failure to train healthcare personnel is an important risk factor for acquiring COVID-19. ABSTRACT Objective: To verify the rate of COVID-19 infection among healthcare personnel at high and low risk of COVID-19 infection and identify the underlying risk factors. Methods: This crosssectional study was conducted between December 1, 2020 and February 28, 2021. Associations […]
Palavras-chave: Infecções por coronavírus; COVID-19; Health personnel; Riscos Ocupacionais; SARS-CoV-2; Transmission
09/maio/2024
Low grip strength and gait speed as markers of dependence regarding basic activities of daily living: the FIBRA study
DOI: 10.31744/einstein_journal/2024AO0637
Highlights A total of 11.7% had concomitant limitations in activities of daily living, slow gait speed, and low muscle strength. Grip strength was not associated with limitations in activities of daily living. Slow gait speed increases the likelihood of limitations in activities of daily living. Gait speed is an essential variable for screening functional decline in older people. ABSTRACT Objective: To determine whether low muscle strength and low gait speed increase the risk of disability related to basic activities of […]
Palavras-chave: Atividades Cotidianas; Idoso; Marcha; Força muscular; Risk factor; Walking speed
09/maio/2024
Retrospective analysis of 1,203 cases of referral to a quaternary vascular surgery outpatient clinic within the Unified Health System, São Paulo, Brazil
einstein (São Paulo). 09/maio/2024;22:eAO0676.
Ver Artigo09/maio/2024
Retrospective analysis of 1,203 cases of referral to a quaternary vascular surgery outpatient clinic within the Unified Health System, São Paulo, Brazil
DOI: 10.31744/einstein_journal/2024AO0676
Highlights Forty-three percent of referrals from basic healthcare units to a specialized vascular surgical service were regarded as inappropriate. The main reasons for inappropriate referrals included study participants without an indication for surgery and those referred to the wrong specialty. A high proportion of inappropriate referrals resulted in the subutilization of highly complex services. Use of telemedicine will assist in reducing the rate of inappropriate referrals. ABSTRACT Objective: Consequently, in this study, we aimed to evaluate 1,203 cases of referral […]
Palavras-chave: Patient-referral systems; Saúde pública; Telemedicina; Tertiary care centers; Vascular surgical procedures
06/maio/2024
Oral candidiasis in liver transplant patients: species identification and antifungal susceptibility profile
einstein (São Paulo). 06/maio/2024;22:eAO0138.
Ver Artigo06/maio/2024
Oral candidiasis in liver transplant patients: species identification and antifungal susceptibility profile
DOI: 10.31744/einstein_journal/2024AO0138
Highlights Fifteen liver transplant patients presented with oral candidiasis. The two prevalent types of candidiasis were atrophic and pseudomembranous. Candida albicans and Candida glabrata were the most prevalent species. Most isolates were susceptible to antifungal agents. ABSTRACT Objective: This study aimed to verify oral candidiasis, identify the causative species, and investigate the antifungal susceptibility of yeasts isolated from liver transplant patients. Methods: A descriptive analysis of 97 patients who underwent liver transplantation was conducted at a hospital. Two clinical examinations […]
Palavras-chave: Antifúngicos; Candida; Candidiasis; Candidíase bucal; Transplante de fígado
06/maio/2024
Hypertensive disorders during pregnancy as a major cause of preterm birth and adverse perinatal outcomes: findings from a Brazilian National Survey
einstein (São Paulo). 06/maio/2024;22:eAO0514.
Ver Artigo06/maio/2024
Hypertensive disorders during pregnancy as a major cause of preterm birth and adverse perinatal outcomes: findings from a Brazilian National Survey
DOI: 10.31744/einstein_journal/2024AO0514
Highlights Pregnant women with increased weight gain must be surveilled for hypertension. Non-white and older women are more likely to develop hypertension. Maternal conditions determine most cases of preterm delivery among women with hypertension. ABSTRACT Objective: This study aimed to evaluate the prevalence of hypertensive disorders during pregnancy among Brazilian women with preterm births and to compare the epidemiological characteristics and perinatal outcomes among preterm births of women with and without hypertension. Methods: This was a secondary cross-sectional analysis of […]
Palavras-chave: Hipertensão; Hypertension, pregnancy-induced; Prematuro; Pre-eclampsia; Pregnancy complications, cardiovascular; Nascimento prematuro
