ABSTRACT Hematopoiesis is characterized by the differentiation and maturation of multipotent stem cells into hematopoietic cells. Common lymphoid progenitor cells differentiate into B and T lymphocytes; natural killer cells can also originate from common lymphoid progenitors. In recent years, a cellular subtype of lymphocytes, called innate lymphocytes, has been described. Innate lymphoid cells (ILCs) play an important effector and regulatory role in innate immunity, and similar to natural killer cells, depend on the γc and Id2 chains for their development. […]

Highlights The relative medians of CD3+, CD4+, and CD8+ T cells were significantly higher in women than in men in a healthy indigenous population. Demographic and ethnic diversity of the Brazilian population can be associated with quantitative modifications in the immunologic cells of healthy individuals. Objective: The establishment of reference values for a subset of leukocytes is common in clinical practice, and ethnic variations are strongly associated with disease development. In Brazil, indigenous people are vulnerable to infections, and few […]

RESUMO Objetivo: Comparar a razão neutrófilo-linfócito e a razão plaqueta-linfócito como possíveis parâmetros de inflamação sistêmica em indivíduos hiperglicêmicos e normoglicêmicos. Métodos: Estudo transversal retrospectivo, em que foram coletados dados dos pacientes que realizaram glicemia em jejum, hemoglobina glicada (HbA1c) e hemograma na mesma data, entre julho e dezembro de 2016. Os pacientes foram divididos em um Grupo Hiperglicêmico e um Grupo Normoglicêmico, pareados por idade e sexo. Os dados foram analisados no Epi Info™, versão 7.2.1.0, em plataforma Windows®. […]