Highlights Autoimmune hepatitis and systemic lupus erythematosus share several clinical features. Anti-P ribosomal antibody is a biomarker for systemic lupus erythematosus. The association between anti-P ribosomal antibody and autoimmune hepatitis has shown conflicting results. Our results showed no association between anti-P ribosomal antibody and autoimmune hepatitis. ABSTRACT Objective: Published studies have shown associations between anti-ribosomal P (anti-P) antibody and systemic lupus erythematosus with hepatic manifestations. This has been reported also in autoimmune hepatitis. However, the consistency of the latter association […]

ABSTRACT Objective Lupus nephritis is one of the most severe complications of systemic lupus erythematosus and it has been estimated that can occur in up to 60% of patients. Direct costs of lupus nephritis have not been studied in developing countries. This study aimed to describe lupus nephritis direct costs in Colombia. Methods Administrative data from two Colombian health maintenance organizations for 2014 and 2015 was obtained. An algorithm based on the International Statistical Classification of Diseases and Related Health […]

Mulher de 42 anos foi encaminhada ao hospital com história de febre e queda do estado geral há 30 dias. À admissão, apresentava taquicardia e sopro sistólico na região apical. Os exames de laboratório mostraram leucocitose com 13.100/mL, hemoglobina 8,4g/dL e anticorpos positivos para lúpus eritematoso sistêmico (anti-Ro/SSA, anti-La/SSB, anticardiolipina e anticorpo antinuclear); hemocultura foi positiva para Streptococcus gallolyticus. Foi realizado um ecocardiograma transesofágico tridimensional, que mostrou múltiplas vegetações na valva mitral, com perfuração do folheto e refluxo importante, além […]