einstein (São Paulo). 14/mar/2025;23:eRW1119.

How the COVID-19 pandemic affected routine child vaccination: an integrative review

Julia Stoeterau

Moré

, Daniel Rodrigo

Serbena

, Luiz Gustavo Gusson de

Camargo

, Pedro Augusto

Clemente

, Fernando Sluchensci dos

Santos

, Juliana Sartori

Bonini

DOI: 10.31744/einstein_journal/2025RW1119

ABSTRACT

Background

Child immunization plays a critical role in preventing numerous diseases. However, the COVID-19) pandemic has profoundly disrupted healthcare systems globally, including routine child vaccination programs.

Objective

To provide an overview of the reduction in vaccine coverage among infants and children during the pandemic and analyze the potential impacts of decreased child immunization during this period.

Methods

A comprehensive search was conducted using the MeSH terms “Child,” “Vaccination”, and “COVID-19,” along with their synonyms. Systematic reviews published between March 11, 2020, and June 1, 2023, in Portuguese or English were included. Databases searched included PubMed, BVS (Biblioteca Virtual em Saúde), Embase, and Scopus. Two blinded independent reviewers performed the selection process, with conflicts resolved by a third reviewer. The AMSTAR-II tool was used to assess the methodological quality of the included studies.

Results

Of the 1,534 eligible articles, only 13 addressed the pandemic’s impact on children’s vaccination coverage. Most studies involved multiple countries and reported a significant decrease in children’s vaccination coverage due to the COVID-19 pandemic.

Conclusion

The findings were heterogeneous but consistently highlighted the substantial impact of the COVID-19 pandemic on routine vaccination coverage in most countries. Further research is needed to explore the epidemiological consequences of disruptions to vaccination schedules, potentially guiding public policies and raising awareness about the importance of adhering to health protection programs.