Highlights ■ Clinical deterioration is a global concern related to patient safety. ■ The Pediatric Alert Score includes assessments of neurological, respiratory, and cardiovascular conditions; temperature; and urine output. ■ The Pediatric Alert Score demonstrated high reliability and strong validity with the B-PEWS-Br. ■ The Pediatric Alert Score is a reliable tool for detecting clinical deterioration and improving patient safety. ABSTRACT Objective: To evaluate the construct validity and reliability of the Pediatric Alert Score in hospitalized children and adolescents. Methods: […]

Highlights ■ Prevalence of HPV16 is extremely low in the tonsil of healthy Brazilian population. ■ The prevalence of HPV16 in oropharyngeal squamous cell carcinoma was 10% in Brazilian samples. ■ The rate of HPV16 tonsillar infection should be lower than that reported previously in Brazil. ABSTRACT Objective: This study aimed to determine the prevalence of human papillomavirus (HPV) 16 infection in the tonsils of patients without cancer and to analyze the associated risk factors in a low-risk population in […]

Highlights ■ Evaluation of a corticosteroid-free antiemetic regimen. ■ Primary endpoint: 46% nausea control. ■ Secondary endpoint: 68% emesis control. ■ Comparable to standard four-drug protocols. ABSTRACT Objective: Chemotherapy-induced nausea and vomiting are highly prevalent adverse events that can lead to poor treatment adherence and a decreased quality of life. To the best of our knowledge, the complete omission of dexamethasone from any regimen for preventing nausea and vomiting has not yet been evaluated. This study aimed to evaluate the […]

Highlights ■ SARS-CoV-2 infection leads to mild-to-moderate disease in children with cystic fibrosis. ■ No worsening of cystic fibrosis was observed months after infection. ABSTRACT Objective: This study aimed to evaluate the clinical manifestations of SARS-CoV-2 in children and adolescents with cystic fibrosis. Methods: This was a case-control analysis of clinical variables and pulmonary function test results in 43 children with cystic fibrosis, 17 (39.5%) of whom tested positive for SARS-CoV-2. Results: The infected children exhibited a higher frequency of […]

Highlights ■ Multiple Mini Interviews assess medical school candidates’ non-cognitive skills effectively. ■ Conscientiousness is found to strongly correlate with higher Multiple Mini Interviews performance. ■ Multiple Mini Interviews ensure diversity without bias toward irrelevant personality traits. ■ Structured interview formats predict academic success and professional readiness. ABSTRACT Objective: To evaluate the effectiveness of Multiple Mini Interviews as a selection method for medical school admissions at the Faculdade Israelita de Ciências da Saúde Albert Einstein by evaluating the relationship between […]

Highlights ■ Teleconsultation reduced on-scene time from 36.8 to 20.6 min (p=0.019). ■ Video-based prearrival anamnesis improved team efficiency. ■ Interventions and clinical profiles were similar across the groups. ■ Study supports broader telemedicine adoption in emergency care. ABSTRACT Objective: Ambulance transport time is an important metric in prehospital care. Limited studies have explored strategies to decrease on-scene time. We examined the effect of collecting telemedicine-based medical data during ambulance dispatch on the on-scene evaluation time of the prehospital team. […]

Highlights ■ The molecular test according to the WHO classification of CNS tumors (gliomas) was performed in 100% (172) of patients. ■ Education on chemotherapy and informed consent for patients with brain tumors was carried out for 100% (130) of the patients who had an indication for chemotherapy treatment. ■ Approximately 87% of the patients with gliomas underwent postoperative cranial MRI. ■ A multidisciplinary approach, including molecular testing, was used for 35% of patients with glioma. ■ Thromboembolic events after […]

Highlights ■ In patients who experienced extubation failure, the total ventilation time was twice as long as that of patients with successful extubation. ■ The incidence of extubation failure was 5.2%, which is relatively low compared to other studies. ■ The study revealed no significant association between the presence of pre-existing illnesses and extubation outcomes. ■ Results indicated that the primary cause of extubation failure was upper airway obstruction, accounting for 67% of cases requiring reintubation. ABSTRACT Objective: To compare […]

Highlights ■ Men with metastatic prostate cancer in the public system have access to fewer treatment lines. ■ Survival in the public system was 3 years shorter than that in the private setting (78 versus 115 months). ABSTRACT Objective: To evaluate the impact of assistance from public and private health systems on the overall survival of patients with metastatic prostate cancer. Methods: A total of 213 patients with metastatic prostate cancer treated at the A.C. Camargo Cancer Center, either in […]

Highlights ■ Gestational trophoblastic disease should be followed up at a referral center. ■ Adequate follow-up improves quality of life for affected women. ■ Multidisciplinary monitoring reduces anxiety and depression in women. ABSTRACT Objective: To evaluate the psychological repercussions of gestational trophoblastic disease. Methods: A cross-sectional study including 100 women (50 with gestational trophoblastic disease and 50 without) was conducted between September 2020 and October 2021. Socio-demographic characteristics, quality of life, depression, and anxiety were evaluated and follow-up was performed […]