Highlights ■ This prospective cohort study assessed prostate biopsy complications in 1,043 men. ■ The major outcomes included bleeding (Clavien-Dindo Grades 2–3 = 1.5%), infections (4.7%), and urinary retention (4.1%). ■ The key risk factors for infection were recent quinolone use, indwelling catheters, and high PSA levels. ■ Acute urinary retention was linked to untreated lower urinary tract symptoms, prostate volume, intravesical prostatic protrusion, and bladder wall thickness. ABSTRACT Objective: To identify complications following transrectal posterior biopsies in a public […]

ABSTRACT Objective: MicroRNAs are small non-coding RNAs that are abundantly expressed in various biofluids, making them promising candidates for cancer biomarkers. This review aims to present current evidence on the use of miRNA as biomarkers for the non-invasive diagnosis of bladder cancer. Methods: A systematic literature review, using the Medline database, was performed in July 2022 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All articles were required to satisfy the risk-of-bias assessment using the Joanna […]

Highlights Multicancer early detection panels are novel assays that allow screening for dozens of cancers using a single blood sample. Data on the optimal workflow for ordering, interpreting, and managing subsequent evaluations of multi-cancer early detection results are lacking. Primary care providers expressed concerns about the cost and management of subsequent evaluations for a positive multicancer early detection test. ABSTRACT Objective Multicancer early detection panels have recently become available to patients with healthcare provider prescriptions and available funds. These tests […]

RESUMO Objetivo Avaliar o impacto da pandemia da COVID-19 no diagnóstico de câncer de mama em um centro de imagem de mama. Métodos Estudo de coorte retrospectivo que incluiu mulheres submetidas a exames e procedimentos de mama em um hospital privado em São Paulo, SP, Brasil, no período de medidas mais rigorosas de isolamento social em 2020 (dividido em primeiro período, de 24 de março a 21 de junho de 2020, e em segundo período, de 22 de junho a […]