Highlights ■ TDF + 3TC + DTG decreases the number of viable stromal vascular cells in subcutaneous adipose tissue. ■ TDF + 3TC + DTG decreases the number of viable stromal vascular cells in visceral adipose tissue. ■ TDF + 3TC + DTG increases leptin and FABP4 expression  in subcutaneous adipose tissue. ABSTRACT Introduction: Several antiretroviral regimens reportedly affect adipose tissue function. While earlier antiretroviral combinations were associated with lipodystrophy, more recent regimens, particularly those containing dolutegravir, have been linked […]

ABSTRACT Agents that inhibit programmed cell death (IPD-1) in T lymphocytes are indicated for patients with advanced cancer. However, some individuals may develop endocrinological conditions, such as diabetes, thyroid dysfunction, and lipodystrophy, after treatment. This systematic review and case report of IPD-1 lipodystrophies describes a patient who received nivolumab treatment for advanced clear cell renal carcinoma and subsequently developed diabetes as well as facial and body lipodystrophy. The patient complained of social distress due to her facial appearance. We treated […]

Highlights Samba rehearsals can increase cardiorespiratory function in dancers up to 19% of VO2max. Samba rehearsals can decrease up to 1.9kg of fat mass and increase 1.3kg of lean body mass. In a samba rehearsal session, dancers spend 50% of their time at an intensity above 83% of the maximum. ABSTRACT Objective: To investigate the effect of 12 weeks of rehearsals on cardiorespiratory parameters and body composition in Brazilian samba dancers belonging to a first-league samba school. Methods: Twenty-six women […]

RESUMO Objetivo Avaliar o efeito do laser de baixa intensidade na proliferação e na viabilidade de células-tronco derivadas de tecido adiposo murinas previamente submetidas à criopreservação. Métodos Células-tronco derivadas de tecido adiposo foram isoladas da região inguinal de três camundongos, submetidas à criopreservação em soro fetal bovino com 10% de dimetilsulfóxido por 30 dias e, depois, descongeladas e mantidas em condições normais de cultivo. As células cultivadas foram irradiadas ou não (controle) com um laser de diodo InGaAIP nos intervalos […]

Objetivo : Avaliar o efeito da terapia com laser de baixa intensidade sobre a proliferação e as possíveis alterações morfológicas nucleares em células-tronco mesenquimais de camundongos. Métodos : Células-tronco mesenquimais derivadas da medula óssea e do tecido adiposo foram submetidas a duas aplicações (T0 e T48 horas) de laser de baixa intensidade (660nm; doses de 0,5 e 1,0J/cm2). O ensaio de azul de tripan foi utilizado para a avaliação da viabilidade celular, e curvas de crescimento foram usadas para avaliar […]