Highlights Approximately 95% of the measles cases reported occurred in unvaccinated individuals. O ur findings revealed that socioeconomic factors influence the spread of the disease. Visual analytics enhanced epidemiological analysis. ABSTRACT Objective: This study aimed to present a temporal and spatial analysis of the 2018 measles outbreak in Brazil, particularly in the metropolitan city of Manaus in the Amazon region, and further introduce a new tool for spatial analysis. Methods: We analyzed the geographical data of the residences of over […]

Highlights Sociodemographic, clinical, and lifestyle factors impact the quality of life of breast cancer survivors. Breast cancer therapy may affect future perspectives and emotional, cognitive, and sexual function. Some aspects of quality of life still require attention from health professionals. ABSTRACT Objective: Patients with cancer often undergo multiple extended treatments that decrease their quality of life. However, the quality of life of women with breast cancer after they undergo treatment remains underexplored in Brazil. Therefore, this study determined sociodemographic, behavioral, […]

Highlights Developed models to forecast bed occupancy for up to 14 days and monitored errors for 365 days. Telemedicine calls from COVID-19 patients correlated withthe number of patients hospitalized in the next 8 days. ABSTRACT Objective: To develop and validate predictive models to estimate the number of COVID-19 patients hospitalized in the intensive care units and general wards of a private not-for-profit hospital in São Paulo, Brazil. Methods: Two main models were developed. The first model calculated hospital occupation as […]

Highlights Higher levels of HIF-1α in patients with peri-implantitis occurred possibly due to persistent hypoxia triggered by inflammation. Tissue hypoxia in peri-implantitis induced increase in HIF-1α consequently increased VEGF and angiogenesis, contributing to the persistence of inflammation. ABSTRACT Objective: This study aimed to compare the levels of HIF1-α, VEGF, TNF-α, and IL-10 in the periimplant crevicular fluid of patients with and without peri-implantitis. Methods: Forty patients, comprising 16 with and 24 without peri-implantitis were selected. Results: Patients with peri-implantitis exhibited […]

Highlights Sitting time increased in 73.9% of women and 84.9% of men at the onset of the pandemic. Physical activity was practiced by 23.9% of women and 39.6% of men at the onset of the pandemic. The prevalence of both women and men reporting physical mobility difficulties increased at follow-up. Hospitalization rates for reasons unrelated to COVID-19 have increased in both women and men. ABSTRACT Objective: This study analyzed the impact of sex on self-reported health and lifestyle parameters in […]

Highlights The overall incidence of febrile neutropenia in the study population was 13.4% (31 cases) Brand-name docetaxel (Taxotere®) use was the only factor associated with the occurrence of febrile neutropenia. No statistically significant differences in progression-free survival rates between brand-name and generic docetaxel. ABSTRACT Objective: To assess the incidence of febrile neutropenia without primary granulocyte colonystimulating factor prophylaxis in patients undergoing chemotherapy with adjuvant docetaxel and cyclophosphamide, and to evaluate the toxicity profile of brand-name docetaxel (Taxotere®) and the generic […]

Highlights Intrathecal chemotherapy did not increase overall survival or time to neurologic deterioration. Compared with no treatment, systemic therapy with no intrathecal chemotherapy afforded better overall survival. Intrathecal chemotherapy should not postpone or preclude systemic treatment. ABSTRACT Objective: To evaluate whether intrathecal chemotherapy improves clinical outcomes in patients with meningeal carcinomatosis. Methods: This retrospective cohort study included consecutive patients with breast cancer diagnosed with meningeal carcinomatosis. Clinical and treatment data were collected from the patients’ medical charts. The primary outcome […]

Highlights Computed tomography revealed fibrotic-like lung changes in 10.9% of patients. Higher computed tomography scores were associated with a reduced DLCO (median computed tomography score, 6 versus 3; p=0.016). Fibrotic-like computed tomography changes were more prevalent in patients with DLCO impairment (p<0.001). Reduced DLCO had sensitivity and specificity of 73% and 88%, respectively, for predicting fibrotic-like computed tomography changes. ABSTRACT Objective: The radiological and functional lung sequelae in COVID-19 survivors remain unclear. We compared the chest computed tomography findings of […]

Highlights Samba rehearsals can increase cardiorespiratory function in dancers up to 19% of VO2max. Samba rehearsals can decrease up to 1.9kg of fat mass and increase 1.3kg of lean body mass. In a samba rehearsal session, dancers spend 50% of their time at an intensity above 83% of the maximum. ABSTRACT Objective: To investigate the effect of 12 weeks of rehearsals on cardiorespiratory parameters and body composition in Brazilian samba dancers belonging to a first-league samba school. Methods: Twenty-six women […]

Highlights Diabetes prevalence at 3.2% among women who had preterm births in Brazil. Almost half of the preterm births of pregnant women with diabetes were therapeutic. Predominance of late preterm cesarean sections with large-for-gestational-age babies. ABSTRACT Objective: The objective was to compare the maternal and perinatal characteristics and outcomes between women with and without diabetes in a Brazilian cohort of women with preterm births. Methods: This was an ancillary analysis of the Brazilian Multicenter Study on Preterm Birth, which included […]