06/nov/2024
Treatment of facial lipodystrophy induced by a biologic agent (IPD-1): a literature review
DOI: 10.31744/einstein_journal/2024RC1111
ABSTRACT Agents that inhibit programmed cell death (IPD-1) in T lymphocytes are indicated for patients with advanced cancer. However, some individuals may develop endocrinological conditions, such as diabetes, thyroid dysfunction, and lipodystrophy, after treatment. This systematic review and case report of IPD-1 lipodystrophies describes a patient who received nivolumab treatment for advanced clear cell renal carcinoma and subsequently developed diabetes as well as facial and body lipodystrophy. The patient complained of social distress due to her facial appearance. We treated […]
Palavras-chave: Tecido adiposo; Apoptose; Carcinoma de células pequenas/quimioterapia; Diabetes mellitus tipo 2; Lipodystrophy; Nivolumab; renal cell; Linfócitos T; Thyroid gland
08/fev/2022
Mammary analogue secretory carcinoma in minor salivary gland
DOI: 10.31744/einstein_journal/2022RC5724
ABSTRACT Mammary analogue secretory carcinoma is a rare neoplasm usually confused with other neoplasms in the salivary glands region. It has great similarity with the breast carcinoma. We report a case of a patient who presented with gingival submucosal bleeding and lesion, with the initial histopathological examination revealing salivary gland neoplasm of low crane. Computed tomography revealed the lesion near the tooth 27, with extension to the floor of the left maxillary sinus and to the palate mucosa. Resection of […]
Palavras-chave: Carcinoma de células pequenas/quimioterapia; Mammary analogue secretory carcinoma; Salivary gland neoplasms; Salivary glands, minor
16/dez/2014
Carcinoma de células pequenas de bexiga
DOI: 10.1590/S1679-45082014RC2975
O carcinoma de células pequenas da bexiga urinária é um tumor extremamente agressivo e raro. Apesar desses tumores terem como sítio principal o pulmão, existem diversos relatos de carcinoma de pequenas células extrapulmonares. Pela baixa frequência, ainda não existe um tratamento bem estabelecido para essa neoplasia. Relatamos o caso de um homem de 61 anos de idade com carcinoma de células pequenas da bexiga urinária que foi submetido à quimioterapia neoadjuvante seguida de cistectomia radical. Fazemos ainda revisão na literatura […]
Palavras-chave: Carcinoma de células pequenas/quimioterapia; Cistectomia/métodos; Neoplasias da bexiga urinária/quimioterapia; Relatos de casos