Highlights ■ Rheumatoid arthritis increases the popliteal lymph node area in rats. ■ Resistance exercise and photobiomodulation modulate  immune cell populations. ■ Both therapies reduce plasma cells and inflammatory cell infiltration. ■ Combined therapy shows no additional benefits over  isolated treatments. ABSTRACT Objective: This study aimed to evaluate the effects of resistance exercise associated with photobiomodulation on the popliteal lymph nodes of Wistar rats subjected to an acute-phase experimental model of rheumatoid arthritis. Methods: The study consisted of 64 male […]

ABSTRACT Objective To evaluate the therapeutic response (functionality) and its associated factors in patients on biological drugs on the Public Health System for treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. Methods An open prospective cohort was carried out from 2011 to 2019, in Belo Horizonte (MG). Functionality was assessed using the Health Assessment Questionnaire Disability-Index at baseline, and after 6 and 12 months of follow-up. Factors associated with poor functionality were identified through logistic regression. Results The median […]

OBJETIVO: Comparar a eficácia e período de uso de tocilizumabe e infliximabe no tratamento de pacientes com artrite reumatoide. MÉTODOS: Foi comparado o tempo de uso de dois biológicos com diferentes mecanismos de ação no tratamento de pacientes com artrite reumatoide. RESULTADOS: Ambos os biológicos se mostraram eficazes, mas o tempo de uso sem perda de eficácia foi maior com tocilizumabe quando comparado ao infliximabe. CONCLUSÃO: Tocilizumabe mantém um período de uso significativamente maior do que infliximabe em pacientes com […]