Volume 17, Number 4, 2019

Vertebral body erosion secondary to aortoiliac aneurysm

Lilian Aguiar Pupo Zanini ORCID logo , André Dubinco ORCID logo , Eduardo Kaiser Ururahy Nunes Fonseca ORCID logo , Fernando Ide Yamauchi ORCID logo , Ronaldo Hueb Baroni ORCID logo

DOI: 10.31744/einstein_journal/2019AI4550

A 75-year old female patient presenting chronic arterial hypertension, was admitted at the emergency department with moderate unspecific abdominal pain. A computed tomography of total abdomen with no contrast enhancement was requested due to altered renal function and suspicion of acute obstructive abdomen. The computed tomography sections ( and ) showed a fusiform aneurysm in the aortoiliac bifurcation, extending up to the right iliac artery. This aneurysm was causing erosion of the anterior aspect of L4 vertebral body, with bone […]

Economic burden of inpatients infected with Klebsiella pneumoniae carbapenemase

Wendel Mombaque dos Santos ORCID logo , Silvia Regina Secoli ORCID logo

DOI: 10.31744/einstein_journal/2019GS4444

ABSTRACT Objective: To estimate the direct medical costs of drug therapy of Klebsiella pneumoniae carbapenemase (KPC) infection patients in hospital-based context. Methods: A cost-of-illness study conducted with a prospective cohort design with hospitalized adults infected by KPC. Data collection was performed using an instrument composed of sociodemographic data, clinical and prescription medication. Estimates of the direct costs associated to each treatment were derived from the payer’s perspective, in the case of federal public hospitals from Brazil, and included only drug […]

Implementing technologies to prevent medication errors at a high-complexity hospital: analysis of cost and results

Renata Prado Bereta Vilela ORCID logo , Marli de Carvalho Jericó ORCID logo

DOI: 10.31744/einstein_journal/2019GS4621

ABSTRACT Objective: To calculate the cost and assess the results on implementing technological resources that can prevent medication errors. Methods: A retrospective, descriptive-exploratory, quantitative study (2007-2015), in the model of case study at a hospital in the Brazilian Southeastern Region. The direct cost of each technology was calculated in the drug chain. Technological efficacy was observed from the reported series of the indicator incidence of medication errors. Results: Thirteen technologies were identified to prevent medication errors. The average cost of […]

Scientific integrity 2.0: misconduct. Let’s prevent, not punish!

Anna Carla Goldberg ORCID logo , Oscar Fernando Pavão dos Santos ORCID logo , Celso Moura Rebello ORCID logo , Jacyr Pasternak ORCID logo

DOI: 10.31744/einstein_journal/2019ED5064

The growing complexity of modern, innovative research has brought up important issues concerning research compliance and responsible conduct of research. The scope of items to be managed have expanded to include a great variety of issues, ranging from authorship, plagiarism, data management, confidentiality, patent rights, conflicts of interest to ethical conduct, animal well-being and social aspects of ongoing research.() All these factors have increasingly burdened the daily routine of wet laboratories, clinical research centers, and animal facilities involved in scientific […]

Medication errors in emergency departments: is electronic medical record an effective barrier?

Marina Vaidotas ORCID logo , Paula Kiyomi Onaga Yokota ORCID logo , Neila Maria Marques Negrini ORCID logo , Dafne Braga Diamante Leiderman ORCID logo , Valéria Pinheiro de Souza ORCID logo , Oscar Fernando Pavão dos Santos ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019GS4282

ABSTRACT Objective: To compare medication errors in two emergency departments with electronic medical record, to two departments that had conventional handwritten records at the same organization. Methods: A cross-sectional, retrospective, descriptive, comparative study of medication errors and their classification, according to the National Coordinating Council for Medication Error Reporting and Prevention, associated with the use of electronic and conventional medical records, in emergency departments of the same organization, during one year. Results: There were 88 events per million opportunities in […]

Peri-prosthetic infection in the postoperative period of endovascular abdominal aorta aneurysm repair: treatment by percutaneous drainage

Diego Lima Nava Martins ORCID logo , Priscila Mina Falsarella ORCID logo , Antonio Rahal Junior ORCID logo , Rodrigo Gobbo Garcia ORCID logo

DOI: 10.31744/einstein_journal/2019RC4668

ABSTRACT Endovascular aneurysm repair is an established technique for treating many infrarenal aortic aneurysms. Infection is one of the most serious complications of this technique, and although percutaneous treatment has been well established for intra-abdominal collections, its use to treat peri-prosthetic fluid collections has not been well determined. In this article we describe a small series of three patients who were treated with percutaneous drainage, with good clinical and imaging responses. Percutaneous drainage is a safe, effective and minimally invasive […]

Dupilumab in the treatment of severe atopic dermatitis refractory to systemic immunosuppression: case report

Mara Huffenbaecher Giavina-Bianchi ORCID logo , Pedro Giavina-Bianchi ORCID logo , Luiz Vicente Rizzo ORCID logo

DOI: 10.31744/einstein_journal/2019RC4599

ABSTRACT Case report of a patient with severe atopic dermatitis who showed a good response to dupilumab. She had already used two immunosuppressive agents, cyclosporine A and mycophenolate mofetil, for the treatment of atopic dermatitis with no proper control of the disease. She had also been taking all measures to control severe cases of the disease: bath and environmental controls, topical potent corticosteroids and emollients. She presented constant pruritus and skin lesions, frequent skin infections e poor quality of life. […]

Evaluation and reconditioning of donor organs for transplantation through ex vivo lung perfusion

Luis Gustavo Abdalla ORCID logo , Karina Andrighetti de Oliveira-Braga ORCID logo , Lucas Matos Fernandes ORCID logo , Marcos Naoyuki Samano ORCID logo , Paula Refinetti Camerini ORCID logo , Paulo Manuel Pêgo-Fernandes ORCID logo

DOI: 10.31744/einstein_journal/2019AO4288

ABSTRACT Objective: To assess the feasibility and impact of ex vivo lung perfusion with hyperoncotic solution (Steen Solution™) in the utilization of these organs in Brazil. Methods: In this prospective study, we subjected five lungs considered to be high risk for transplantation to 4 hours of ex vivo lung perfusion, with evaluation of oxygenation capacity. High-risk donor lungs were defined by specific criteria, including inflammatory infiltrates, pulmonary edema and partial pressure of arterial oxygen less than 300mmHg (inspired oxygen fraction […]