Volume 16, Number 2, April/June 2018

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosis of mediastinal lesions

Ricardo Sales dos Santos, Marcia Jacomelli, Juliana Pereira Franceschini, Iunis Suzuki, Altair da Silva Costa Jr., Christina Shiang, [...]

DOI: 10.1590/S1679-45082018AO4094

ABSTRACT Objective To describe the results of endobronchial ultrasound-guided transbronchial needle aspiration in making diagnosis of mediastinal injuries associated to different causes. Methods A retrospective cross-sectional study of patients submitted to Endobronchial ultrasound-guided transbronchial needle aspiration at a private organization, between June 2013 and October 2016. All cases referred for collection of lymph nodes or peritracheal/peribronchial masses by endobronchial ultrasound-guided transbronchial needle aspiration, and evaluated through tomography or PET-CT were included. Interventional pulmonologists and thoracic surgeons with experience in the […]

Influence of growth hormone replacement on neurological and psychomotor development. Case report

Felipe Motta, Adriana Pasmanik Eisencraft, Lindiane Gomes Crisostomo

DOI: 10.1590/S1679-45082018RC3961

ABSTRACT The height response to the use of growth hormone in short height cases has already been confirmed in the literature. The influence of the insulin-like growth factor 1 (GH-IGF1) axis components on development, function, regeneration, neuroprotection, cognition, and motor functions has been evaluated in experimental studies and in adults with central nervous system lesions. However, there is still little research on the clinical impact of hormone replacement on neurological and psychomotor development. This report presents the case of a […]

Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla

Hellen Bandeira de Pontes Santos, Aníbal Henrique Barbosa de Luna, Pedro Everton Marques Goes, Alexander Tadeu Sverzut, Cassiano Francisco Weege Nonaka, Pollianna Muniz Alves

DOI: 10.1590/S1679-45082018RC4025

ABSTRACT Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. The presumptive diagnoses were dentigerous cyst, adenomatoid odontogenic tumor, melanotic neuroectodermal tumor of infancy and rhabdomyosarcoma, and an incisional biopsy was performed. Microscopically, the lesion revealed a biphasic cell population, consisting of […]

Qualitative assessment of online information about age-related macular degeneration available in Portuguese

Jorge Agi, Niro Kasahara, Claudio Luiz Lottenberg

DOI: 10.1590/S1679-45082018AO4240

ABSTRACT Objective: To evaluate the quality of online information on age-related macular degeneration available in Portuguese. Methods: The search term “age-related macular degeneration” was used to browse the web using four different search engines. The first 40 websites appearing on match lists provided by each search engine were recorded and those listed in at least three tab pages selected. The Sandvik Severity Index was used as to assess website quality. Results: Quality of information available on selected websites was rated […]

The importance of dysphagia screening and nutritional assessment in hospitalized patients

Patrícia Amaro Andrade, Carolina Araújo dos Santos, Heloísa Helena Firmino, Carla de Oliveira Barbosa Rosa

DOI: 10.1590/S1679-45082018AO4189

ABSTRACT Objective: To determine frequency of dysphagia risk and associated factors in hospitalized patients as well as to evaluate nutritional status by using different methods and correlate the status with scores of the Eating Assessment Tool (EAT-10). Methods: This was a cross-sectional study including 909 inpatients of a philanthropic hospital. For the diagnosis of dysphagia we used an adapted and validated Brazilian version of the Eating Assessment Tool (EAT-10). The nutritional status was evaluated through the subjective global assessment, and […]

X-linked spinal and bulbar muscular atrophy (Kennedy’s disease): the first case described in the Brazilian Amazon

Camila Nascimento Alves, Tiago Kiyoshi Kitabayashi Braga, Danusa Neves Somensi, Bruno Sérgio Vilhena do Nascimento, José Antônio Santos de Lima, Satomi Fujihara

DOI: 10.1590/S1679-45082018RC4011

ABSTRACT The X-linked spinal and bulbar muscular atrophy (Kennedy’s disease) is a rare X-linked, recessive, lower motor neuron disease, characterized by weakness, atrophy, and fasciculations of the appendicular and bulbar muscle. The disease is caused by an expansion of the CAG repetition in the androgen receptor gene. Patients with Kennedy’s disease have more than 39 CAG repetitions. We report a case of 57-year-old man, resident of Monte Dourado (PA, Brazil) who complained of brachiocrural paresis evolving for 3 years along […]

Standardization of the infusion sequence of antineoplastic drugs used in the treatment of breast and colorectal cancers

Amanda Alves da Silva, Juliane Carlotto, Inajara Rotta

DOI: 10.1590/S1679-45082018RW4074

ABSTRACT The definition of antineoplastic administration sequences can help planning of therapeutic regimens in a more rational way, and thus optimize chemotherapy effects on patients, increasing efficacy and reducing toxic effects. In this way, this study aimed to evaluate the infusion order of antineoplastic agents of the main therapeutic protocols used in the treatment of colorectal and breast cancer which are used in a tertiary hospital, identifying possible interactions dependent on the infusion sequence. For the definition of protocols adopted […]

Cardiovascular risk and use of conicity index in patients submitted to autologous hematopoietic stem cell transplantation

Suelyne Rodrigues de Morais, Ana Carolina Cavalcante Viana, Ana Filomena Camacho Santos Daltro, Priscila da Silva Mendonça

DOI: 10.1590/S1679-45082018AO4253

ABSTRACT Objective To analyze the prevalence of overweight and the use of conicity index for cardiovascular risk assessment in individuals submitted to autologous hematopoietic stem cell transplantation. Methods The sample comprised 91 patients of both sexes, who underwent autologous hematopoietic stem cell transplantation from September 2008 to December 2013, aged 18 years or over. To determine the nutritional profile, we collected anthropometric data on weight, height, waist circumference upon hospital admission. The body mass index and the conicity index were […]

Challenge, Discussion and Conclusion: an active teaching strategy to turn traditional lectures into collaborative classes

Welbert Oliveira Pereira, Fernanda Teresa Lima

DOI: 10.1590/S1679-45082018ED4362

D2R: step by step Just as with other active strategies, a D2R interactive class requires some pillars that enable preparing the students (therefore it is necessary to provide study material in advance), group projects (it is fundamental to divide the students into teams before class), and practical application of the content (the teacher prepares and presents cases and issues that simulate the practical application of the class, avoiding the valid question of students “Why do I need to learn this?”). […]

Incidence of variant hemoglobins in newborns attended by a public health laboratory

Flávia Mylla de Sousa Reis, Renata Rodrigues de Oliveira Castelo Branco, Amanda Mota Conceição, Letícia Paula Benvindo Trajano, José Felipe Pinheiro do Nascimento Vieira, Pablo Ricardo Barbosa Ferreira, [...]

DOI: 10.1590/S1679-45082018AO4150

ABSTRACT Objective To evaluate the incidence of variant hemoglobins in different health regions. Methods A descriptive, observational, and cross-sectional study with a quantitative approach based on secondary data in the internal records of the neonatal screening service – Laboratório Central de Saúde Pública do Estado do Piauí (PI, Brazil). The variables related to sex, ethnicity and positive diagnosis for variant hemoglobins were analyzed, with further population distribution of hemoglobinopathies among the macroregions of the state. Results A total of 69,180 […]

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