Volume 15, Number 3, July/September 2017

Mediastinal tumor: not always a lymphoma

Silvia Mansur Reimão, Rogério Colaiacovo, Marco Antonio Ribeiro Camunha, Thiago Trolez Amancio, Vanderlei Segatelli, Gustavo Andrade de Paulo

DOI: 10.1590/S1679-45082017AI3981

A 45-year-old male patient, hospitalized and under investigation of mediastinal mass, presenting with sudoresis, malaise, and dysphagia. Computed tomography showed eccentric parietal thickening of the middle third of esophagus, with mass effect and upstream ectasia, with no expressive increase of metabolic activity. Additionally, there are cervical, axillary, pulmonary hilar, portocaval space, and unspecific iliac lymph nodes ( and ). […]

Incidental finding in a newborn with respiratory distress

Natália Noronha, Pedro Pires Epifânio, Patrícia Vaz Silva, António Pires, António Marinho, Eduardo Castela

DOI: 10.1590/S1679-45082017AI4001

A full-term 1-day-old male newborn was admitted to the neonatal intensive care unit due to respiratory distress and cyanosis. The sepsis screen was negative and he was diagnosed as transient tachypnea of the newborn. He required supplemental oxygen for the following days and the sepsis screen was repeated and was negative. He remained in respiratory distress, particularly during feeding, and was referred to a pediatric cardiologist. On transthoracic echocardiography, the heart appeared to be structurally and functionally normal. However the […]

Successful treatment of post-transplant relapsed acute myeloid leukemia with FLT3 internal tandem duplication using the combination of induction chemotherapy, donor lymphocyte infusion, sorafenib and azacitidine. Report of three cases

Paulo Vidal Campregher, Vinicius Renan Pinto de Mattos, Marco Aurélio Salvino, Fabio Pires de Souza Santos, Nelson Hamerschlak

DOI: 10.1590/S1679-45082017RC3784

ABSTRACT Acute myeloid leukemia is a hematopoietic stem cell neoplastic disease associated with high morbidity and mortality. The presence of FLT3 internal tandem duplication mutations leads to high rates of relapse and decreased overall survival. Patients with FLT3 internal tandem duplication are normally treated with hematopoietic stem cell transplantation in first complete remission. Nevertheless, the incidence of post-transplant relapse is considerable in this group of patients, and the management of this clinical condition is challenging. The report describes the outcomes […]

The therapeutic challenge of giant splenic artery aneurysm: a case repport

Paulo Kauffman, Antonio Luiz de Vasconcellos Macedo, Roberto Sacilotto, Adriano Tachibana, Sergio Kuzniec, Lucas Lembrança Pinheiro, [...]

DOI: 10.1590/S1679-45082017RC3873

ABSTRACT Giant splenic artery aneurysm is a rare condition that represents an eminent life threatening for the patient, requiring, therefore, urgent surgical correction. A 61-year-old woman, former smoker, hypertensive, hypercholesterolemic and multipara sought our service because of a large tumor in the mesogastrium, which was an abdominal ultrasound finding. Despite the size of the tumor, the patient was asymptomatic. The angiotomography and the magnetic resonance image of the abdomen were suggestive of giant splenic artery aneurysm with more than 10cm […]

Intrapancreatic accessory spleen

Marcelo Protásio dos Santos, Aline Pacheco de Rezende, Paulo Vicente dos Santos Filho, José Eduardo Gonçalves, Fernando Bray Beraldo, Adriano Pereira Sampaio

DOI: 10.1590/S1679-45082017RC3942

ABSTRACT An asymptomatic 79-year-old woman, with incidental finding on abdominal ultrasound of a solid nodule in the tail of the pancreas. Magnetic resonance imaging showed a 12mm solid tumor. The suggested diagnosis was pancreatic neuroendocrine tumor. The pathological examination showed an intrapancreatic splenic tissue. This is a rare ectopic location of spleen tissue and it should be considered in the differential diagnosis of pancreatic solid tumors.

A new era of thromboelastometry

Tomaz Crochemore, Felipe Maia de Toledo Piza, Roseny dos Reis Rodrigues, João Carlos de Campos Guerra, Leonardo José Rolim Ferraz, Thiago Domingos Corrêa

DOI: 10.1590/S1679-45082017MD3130

ABSTRACT Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the use of allogeneic blood components, and in this way, preventing an occurrence of their potential adverse effects. Conventional coagulation tests such as prothrombin time and activated partial thromboplastin time present limitations in predicting bleeding and guiding transfusion therapy in […]

New US Preventive Service Task Force recommendations for prostate cancer screening: a needed update, but not enough

Marcelo Langer Wroclawski

DOI: 10.1590/S1679-45082017ED4151

Prostate cancer (PC) screening remains a controversial topic, although it has been studied for more than two decades. Since the 1990s, when the use of Prostate-Specific Antigen (PSA) began in clinical practice, the mortality rate from PC has decreased by around 50%. Prostate cancer screening policies, early diagnosis and treatment are pointed out as responsible to 45%-70% of this reduction.() On the other hand, indiscriminate screening can lead to problems because of unnecessary prostate biopsies, and their possible side effects, […]


Jacyr Pasternak

DOI: 10.1590/S1679-45082017ED4239

We all are amazed by the extent of corruption in our political system. We believe corruption is frequent or even the norm, such as to receive money from private construction companies that build for the government, exchanging favors and money for politicians. As an excuse, some entrepreneurs declared that without these favors they would never get the contracts… The corrupted politicians said that without the money given by these companies, they would be unable to pay for their election campaigns, […]

The effects of cigarette smoking on ventricular repolarization in adolescents

Seyma Kayali, Fadime Demir

DOI: 10.1590/S1679-45082017AO3945

ABSTRACT Objective To assess the association between cigarette smoking and ventricular arrhythmias in adolescents. Novel electrocardiographic parameters –Tp-e interval, as well as Tpe/QT and Tpe/QTc ratios – were used to make this assessment. Methods The study population consisted of 87 subjects aged between 16-19 years. Fifty-one adolescent smokers with no risk of arrhythmia comprised the Smoker Group, and 36 adolescents who had never smoked cigarettes comprised the Control Group. Smokers were defined as patients smoking more than three cigarettes per […]

Analysis of colostrum IgA against bacteria involved in neonatal infections

Elizabeth Moreira Dias, Denise Bertulucci Rocha Rodrigues, Vinícius Rangel Geraldo-Martins, Ruchele Dias Nogueira

DOI: 10.1590/S1679-45082017AO3958

ABSTRACT Objective To describe e compare the specificity of IgA antibodies against bacteria extract of Klebsiella pneumoniae , Staphylococcus aureus , Escherichia coli , and Salmonella enteritidis . Methods Colostrum samples were aseptically collected in the first 12 hours after C-section delivery. The specificity of IgA against bacteria extracts was analyzed by the Western blot. Results The findings showed proteins of high molecular weight frequently detectable in the samples. S. aureus was the most frequently found bacterium in the samples […]

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