Volume 15, Number 3, July/September 2017

New US Preventive Service Task Force recommendations for prostate cancer screening: a needed update, but not enough

Marcelo Langer Wroclawski

DOI: 10.1590/S1679-45082017ED4151

Prostate cancer (PC) screening remains a controversial topic, although it has been studied for more than two decades. Since the 1990s, when the use of Prostate-Specific Antigen (PSA) began in clinical practice, the mortality rate from PC has decreased by around 50%. Prostate cancer screening policies, early diagnosis and treatment are pointed out as responsible to 45%-70% of this reduction.() On the other hand, indiscriminate screening can lead to problems because of unnecessary prostate biopsies, and their possible side effects, […]


Jacyr Pasternak

DOI: 10.1590/S1679-45082017ED4239

We all are amazed by the extent of corruption in our political system. We believe corruption is frequent or even the norm, such as to receive money from private construction companies that build for the government, exchanging favors and money for politicians. As an excuse, some entrepreneurs declared that without these favors they would never get the contracts… The corrupted politicians said that without the money given by these companies, they would be unable to pay for their election campaigns, […]

The effects of cigarette smoking on ventricular repolarization in adolescents

Seyma Kayali, Fadime Demir

DOI: 10.1590/S1679-45082017AO3945

ABSTRACT Objective To assess the association between cigarette smoking and ventricular arrhythmias in adolescents. Novel electrocardiographic parameters –Tp-e interval, as well as Tpe/QT and Tpe/QTc ratios – were used to make this assessment. Methods The study population consisted of 87 subjects aged between 16-19 years. Fifty-one adolescent smokers with no risk of arrhythmia comprised the Smoker Group, and 36 adolescents who had never smoked cigarettes comprised the Control Group. Smokers were defined as patients smoking more than three cigarettes per […]

Analysis of colostrum IgA against bacteria involved in neonatal infections

Elizabeth Moreira Dias, Denise Bertulucci Rocha Rodrigues, Vinícius Rangel Geraldo-Martins, Ruchele Dias Nogueira

DOI: 10.1590/S1679-45082017AO3958

ABSTRACT Objective To describe e compare the specificity of IgA antibodies against bacteria extract of Klebsiella pneumoniae , Staphylococcus aureus , Escherichia coli , and Salmonella enteritidis . Methods Colostrum samples were aseptically collected in the first 12 hours after C-section delivery. The specificity of IgA against bacteria extracts was analyzed by the Western blot. Results The findings showed proteins of high molecular weight frequently detectable in the samples. S. aureus was the most frequently found bacterium in the samples […]

Static and dynamic balance of children and adolescents with sensorineural hearing loss

Renato de Souza Melo, Sônia Elvira dos Santos Marinho, Maryelly Evelly Araújo Freire, Robson Arruda Souza, Hélio Anderson Melo Damasceno, Maria Cristina Falcão Raposo

DOI: 10.1590/S1679-45082017AO3976

ABSTRACT Objective To assess the static and dynamic balance performance of students with normal hearing and with sensorineural hearing loss. Methods A cross-sectional study assessing 96 students, 48 with normal hearing and 48 with sensorineural hearing loss of both sexes, aged 7 and 18 years. To evaluate static balance, Romberg, Romberg-Barré and Fournier tests were used; and for the dynamic balance, we applied the Unterberger test. Results Hearing loss students showed more changes in static and dynamic balance as compared […]

How polymorphic markers contribute to genetic diseases in different populations? The study of inhibin A for premature ovarian insufficiency

Denise Maria Christofolini, Emerson Barchi Cordts, Fernando Santos-Pinheiro, Erika Azuma Kayaki, Mayla Cristina Fernandes Dornas, Monise de Castro Santos, [...]

DOI: 10.1590/S1679-45082017AO4052

ABSTRACT Objective To verify the incidence of the G679A mutation in exon 2 of the gene inhibin alpha (INHA), in women with secondary amenorrhea and diagnosis of premature ovarian insufficiency, and in controls. Methods A 5mL sample of peripheral blood was collected from all study participants in an EDTA tube and was used for DNA extraction. For the patient group, 5mL of blood were also collected in a tube containing heparin for karyotype, and 5mL were collected in a dry […]

Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques

Renato de Oliveira, Fernanda Godoy Cabral, Waldemar de Almeida Pereira Carvalho, Emerson Barchi Cordts, Bianca Bianco, Caio Parente Barbosa

DOI: 10.1590/S1679-45082017AO4091

ABSTRACT Objective To evaluate the predictive capacity for pregnancy of the progesterone level on the day of administering human chorionic gonadotropin, in women submitted to assisted reproductive techniques. Methods An observational study with 914 women submitted to assisted reproductive techniques from August 2014 to June 2016. Results Total pregnancy rate was 34.58%; in that, the pregnancy rate in women 38 years was, respectively, 42.3%, 38.7% and 16.1% (p

Relation between functional mobility and dynapenia in institutionalized frail elderly

Antonio Vinicius Soares, Elessandra Marcelino, Késsia Cristina Maia, Noé Gomes Borges Junior

DOI: 10.1590/S1679-45082017AO3932

ABSTRACT Objective To investigate the relation between functional mobility and dynapenia in institutionalized frail elderly. Methods A descriptive, correlational study involving 26 institutionalized elderly men and women, mean age 82.3±6 years. The instruments employed were the Mini Mental State Examination, the Geriatric Depression Scale, the International Physical Activity Questionnaire, the Timed Up and Go test, a handgrip dynamometer and a portable dynamometer for large muscle groups (shoulder, elbow and hip flexors, knee extensors and ankle dorsiflexors). Results Significant negative correlation […]

Interventions of the clinical pharmacist in an Intermediate Care Unit for elderly patients

Stéphanie de Souza Costa Viana, Tiago Arantes, Sabrina Corrêa da Costa Ribeiro

DOI: 10.1590/S1679-45082017AO3894

ABSTRACT Objective To discuss the role of the clinical pharmacist in hospital care of critical elderly patients. Methods Critical patients aged 60 years and over admitted by the clinical staff to an Intermediate Care Unit were followed-up for 4 months regarding their drug therapies. Medical prescriptions were reviewed daily on the basis of patients’ clinical conditions, with the view to identify opportunities for optimization of drug therapies, contributing to safer prescribing, reduced discomfort and correct and rational use of drugs. […]

Maintenance of exercise training benefits is associated with adequate milk and dairy products intake in elderly hypertensive subjects following detraining

Wilson Max Almeida Monteiro de Moraes, Neucilane Silveira dos Santos, Larissa Pereira Aguiar, Luís Gustavo Oliveira de Sousa

DOI: 10.1590/S1679-45082017AO4048

ABSTRACT Objective To investigate whether maintenance of exercise training benefits is associated with adequate milk and dairy products intake in hypertensive elderly subjects after detraining. Methods Twenty-eight elderly hypertensive patients with optimal clinical treatment underwent 16 weeks of multicomponent exercise training program followed by 6 weeks of detraining, and were classified according to milk and dairy products intake as low milk (

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