Volume 13, Number 3, July/September 2015

Higher overall survival in metastatic pancreatic cancer: the impact of where and how treatment is delivered

Pedro Luiz Serrano Usón Junior, Monique Sedlmaier França, Heloisa Veasey Rodrigues, Antônio Luiz de Vasconcellos Macedo, Alberto Goldenberg, Oren Smaletz, [...]

DOI: 10.1590/S1679-45082015AO3303

ObjectiveTo determine the overall survival of patients with advanced pancreatic cancer and evaluate factors that impact prognosis in a private cancer center.MethodsData from the Hospital Cancer Registry at Hospital Israelita Albert Einstein were retrospectively collected. The patients enrolled had metastatic cancer at diagnosis or earlier staging and subsequent recurrence. Cases of neuroendocrine tumors were excluded.ResultsA total of 65 patients were evaluated, including 63 with adenocarcinoma. The median overall survival for patients in all stages was 20.7 months (95%CI: 15.6-25.7), while […]

Chronic psychological stress and its impact on the development of aggressive breast cancer

Thayse Fachin Cormanique, Lirane Elize Defante Ferreto de Almeida, Cynthia Alba Rech, Daniel Rech, Ana Cristina da Silva do Amaral Herrera, Carolina Panis

DOI: 10.1590/S1679-45082015AO3344

ObjectiveTo investigate the clinicopathological findings of women diagnosed with breast cancer and study the impact of chronic psychological stress on the pathological characteristics of these tumors.MethodsWe investigated a cohort composed of women diagnosed with breast cancer and divided into two groups. One group was categorized as presenting with chronic psychological stress (by using the Self-Reporting Questionnaire − SRQ-20). Another group of women with breast cancer, but with no previous history of chronic psychological stress, comprised the Control Group. Clinical and […]

Body surface infrared thermometry in patients with central venous cateter-related infections

José Henrique Silvah, Cristiane Maria Mártires de Lima, Maria do Rosário Del Lama de Unamuno, Marco Antônio Alves Schetino, Luana Pereira Leite Schetino, Priscila Giácomo Fassini, [...]

DOI: 10.1590/S1679-45082015AO3397

ObjectiveTo evaluate if body surface temperature close to the central venous catheter insertion area is different when patients develop catheter-related bloodstream infections.MethodsObservational cross-sectional study. Using a non-contact infrared thermometer, 3 consecutive measurements of body surface temperature were collected from 39 patients with central venous catheter on the following sites: nearby the catheter insertion area or totally implantable catheter reservoir, the equivalent contralateral region (without catheter), and forehead of the same subject.ResultsA total of 323 observations were collected. Respectively, both in […]

Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil

Alexandre de Matos Soeiro, Felipe Lourenço Fernandes, Maria Carolina Feres de Almeida Soeiro, Carlos Vicente Serrano Jr, Múcio Tavares de Oliveira Jr

DOI: 10.1590/S1679-45082015AO3381

ObjectiveIn Brazil, there are few descriptions in the literature on the angiographic pattern and clinical characteristics of young patients with acute coronary syndrome, despite the evident number of cases in the population. The objective of this study was to evaluate which clinical characteristics are most closely related to the acute coronary syndrome in young patients, and what long-term outcomes are in this population.MethodsThis is a prospective observational study with 268 patients aged under 55 years with acute coronary syndrome, carried […]

Agreement in cardiovascular risk rating based on anthropometric parameters

Endilly Maria da Silva Dantas, Cristiane Jordânia Pinto, Rodrigo Pegado de Abreu Freitas, Anna Cecília Queiroz de Medeiros

DOI: 10.1590/S1679-45082015AO3349

ObjectiveTo investigate the agreement in evaluation of risk of developing cardiovascular diseases based on anthropometric parameters in young adults.MethodsThe study included 406 students, measuring weight, height, and waist and neck circumferences. Waist-to-height ratio and the conicity index. The kappa coefficient was used to assess agreement in risk classification for cardiovascular diseases. The positive and negative specific agreement values were calculated as well. The Pearson chi-square (χ2) test was used to assess associations between categorical variables (p

Previous blood pressure measurement and associated factors in student adolescents

Marina Gabriella Pereira de Andrada Magalhães, Breno Quintella Farah, Mauro Virgilio Gomes de Barros, Raphael Mendes Ritti-Dias

DOI: 10.1590/S1679-45082015AO3358

ObjectiveTo identify prevalence of previous blood pressure measurement and analyze some associated factors in adolescents.MethodsThis cross-sectional study included 6,077 adolescents aged 14 to 19 years. Demographic characteristics included (sex, age, period of study, region of residence, work, skin color, and economic) status, history of blood pressure measurement within last 12 months, local of blood pressure measurement, and reading obtained. To assess associations between previous blood pressure measurement with demographic characteristics and high blood pressure we used descriptive statistics and logistic […]

Multidisciplinary intervention in obese adolescents: predictors of dropout

Yara Lucy Fidelix, José Cazuza de Farias Júnior, Mara Cristina Lofrano-Prado, Ricardo Luís Fernandes Guerra, Michelle Cardel, Wagner Luiz do Prado

DOI: 10.1590/S1679-45082015AO3339

ObjectiveTo identify biological and psychosocial factors associated with dropout in a multidisciplinary behavioral intervention in obese adolescents.MethodsA total of 183 adolescents (15.4±1.6 years), pubertal (Tanner stage 3 or 4) and obese (34.7±4.0kg/m2), were enrolled in a 12-week behavioral intervention, which included clinical consultations (monthly), nutritional and psychological counseling (once a week), and supervised aerobic training (three times/week). The studied variables were weight, height, body mass index, body composition (skinfold), cardiorespiratory fitness (direct gas analysis), blood lipids and self-reported symptoms of […]

Long-lasting endothelium-dependent relaxation of isolated arteries caused by an extract from the bark of Combretum leprosum

Francisco das Chagas Alves Filho, Paulo Marques da Silva Cavalcanti, Rita de Cassia Aleixo Tostes Passaglia, Gustavo Ballejo

DOI: 10.1590/S1679-45082015AO3242

ObjectiveTo describe and to characterize the relaxing effect of an extract of the bark of Combretum leprosum on isolated arterial rings from different animals.MethodsRings (3 to 4mm) from rabbit, rat, or porcine arteries rings were suspended in an organ bath (Krebs, 37°C, 95%O2/5%CO2) to record isometric contractions. After the stabilization period (2 to 3 hours) contractions were induced by the addition of phenylephrine (0.1 to 0.3µM) or U46619 (10 to 100nM), and Combretum leprosum extract was added on the plateau […]

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