Volume 13, Number 2, April/June 2015

Lung transplantation

José Eduardo Afonso Júnior, Eduardo de Campos Werebe, Rafael Medeiros Carraro, Ricardo Henrique de Oliveira Braga Teixeira, Lucas Matos Fernandes, Luis Gustavo Abdalla, [...]

DOI: 10.1590/S1679-45082015RW3156

ABSTRACTLung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil. However, survival of the transplant is less than desired, with a high mortality rate related to primary graft dysfunction, infection, and chronic graft dysfunction, particularly in the form of bronchiolitis obliterans syndrome. New […]

Pancreas transplantation: review

Roberto Ferreira Meirelles Júnior, Paolo Salvalaggio, Alvaro Pacheco-Silva

DOI: 10.1590/S1679-45082015RW3163

ABSTRACTVascularized pancreas transplantation is the only treatment that establishes normal glucose levels and normalizes glycosylated hemoglobin levels in type 1 diabetic patients. The first vascularized pancreas transplant was performed by William Kelly and Richard Lillehei, to treat a type 1 diabetes patient, in December 1966. In Brazil, Edison Teixeira performed the first isolated segmental pancreas transplant in 1968. Until the 1980s, pancreas transplants were restricted to a few centers of the United States and Europe. The introduction of tacrolimus and […]

Heart transplantation: review

Sandrigo Mangini, Bárbara Rubim Alves, Odílson Marcos Silvestre, Philippe Vieira Pires, Lucas José Tachotti Pires, Milena Novaes Cardoso Curiati, [...]

DOI: 10.1590/S1679-45082015RW3154

ABSTRACTHeart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, […]

Expanding the pool of kidney donors: use of kidneys with acute renal dysfunction

Ana Cristina Carvalho de Matos, Lúcio Roberto Requião-Moura, Gabriela Clarizia, Marcelino de Souza Durão Junior, Eduardo José Tonato, Rogério Chinen, [...]

DOI: 10.1590/S1679-45082015RW3147

ABSTRACTGiven the shortage of organs transplantation, some strategies have been adopted by the transplant community to increase the supply of organs. One strategy is the use of expanded criteria for donors, that is, donors aged >60 years or 50 and 59 years, and meeting two or more of the following criteria: history of hypertension, terminal serum creatinine >1.5mg/dL, and stroke as the donor´s cause of death. In this review, emphasis was placed on the use of donors with acute renal […]

Liver-specific magnetic resonance contrast medium in the evaluation of chronic liver disease

Marcio Augusto Correia Rodrigues dos Reis, Ronaldo Hueb Baroni

DOI: 10.1590/S1679-45082015RW3159

ABSTRACTThe hepatobiliary-specific contrast medium (gadoxetic acid – Primovist®) is primarily used to improve detection and characterization of focal hepatic lesions, such as in chronic liver disease patients with suspected hepatocellular carcinoma. Since the contrast medium is selectively taken up by functioning hepatocytes in the late hepatobiliary phase, it helps to detect typical hepatocellular carcinoma, which show low signal intensity on this phase. This imaging feature also assists in differentiating regenerative/dysplastic nodules from early hepatocellular carcinomas (with over 90% accuracy), as […]

Clinical aspects of influenza A(H1N1)pdm09 cases reported during the pandemic in Brazil, 2009-2010

Érika Valeska Rossetto, Expedito José de Albuquerque Luna

DOI: 10.1590/S1679-45082015AO3331

ABSTRACTObjective:To describe the clinical aspects of cases of influenza A(H1N1)pdm09 in Brazil.Methods:A descriptive study of cases reported in Sistema de Informação de Agravos de Notificação (SINAN), 2009-2010.Results:As the final classification, we obtained 53,797 (56.79%) reported cases confirmed as a new influenza virus subtype, and 40,926 (43.21%) cases discarded. Fever was the most common sign, recorded in 99.74% of the confirmed and 98.92% of the discarded cases. Among the confirmed cases, the presence of comorbidities was reported in 32.53%, and in […]

One-year follow-up of neurological status of patients after cardiac arrest seen at the emergency room of a teaching hospital

Cássia Regina Vancini-Campanharo, Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Maria Carolina Barbosa Teixeira Lopes, Meiry Fernanda Pinto Okuno, Ruth Ester Assayag Batista, [...]

DOI: 10.1590/S1679-45082015AO3286

ABSTRACTObjective:To describe neurological status and associated factors of survivors after cardiac arrest, upon discharge, and at 6 and 12 month follow-up.Methods:A cohort, prospective, descriptive study conducted in an emergency room. Patients who suffered cardiac arrest and survived were included. A one-year consecutive sample, comprising 285 patients and survivors (n=16) followed up for one year after discharge. Neurological status was assessed by the Cerebral Performance Category before the cardiac arrest, upon discharge, and at 6 and 12 months after discharge. The […]

Characteristics of an outpatient chronic hepatitis B virus infection cohort

Danyenne Rejane de Assis, Simone de Barros Tenore, João Renato Rebello Pinho, David Salomão Lewi, Paulo Roberto Abrão Ferreira

DOI: 10.1590/S1679-45082015AO3269

ABSTRACTObjective:To characterize a chronic hepatitis B cohort based on initial and follow-up clinical evaluations.Methods:A retrospective and descriptive analysis of clinical and laboratory data from chronic HBsAg adult carriers, without HIV, unexposed to treatment, with at least two outpatient visits, between February 2006 and November 2012. Fisher´s exact test, χ², Wilcoxon, Spearman, multiple comparisons and Kappa tests were applied, the level of significance adopted was 5%, with a 95% confidence interval.Results:175 patients with mean age of 42.95±12.53 years were included: 93 […]

Check-up and cardiovascular risk progression: is there a room for innovation?

Raquel Dilguerian de Oliveira Conceição, Antonio Gabriele Laurinavicius, Nea Miwa Kashiwagi, José Antonio Maluf de Carvalho, Carlos Alberto Garcia Oliva, Raul Dias Santos Filho

DOI: 10.1590/S1679-45082015AO3216

ABSTRACTObjective:To evaluate the impact of traditional check-up appointment on the progression of the cardiovascular risk throughout time.Methods:This retrospective cohort study included 11,126 medical records of asymptomatic executives who were evaluated between January, 2005 and October, 2008. Variables included participants’ demographics characteristics, smoking habit, history of cardiovascular diseases, diabetes, dyslipidemia, total cholesterol, HDL, triglycerides, glucose, c-reactive protein, waist circumference, hepatic steatosis, Framingham score, metabolic syndrome, level of physical activity, stress, alcohol consumption, and body mass index.Results:A total of 3,150 patients was […]

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