Volume 13, Number 2, April/June 2015

Clinical aspects of influenza A(H1N1)pdm09 cases reported during the pandemic in Brazil, 2009-2010

Érika Valeska Rossetto, Expedito José de Albuquerque Luna

DOI: 10.1590/S1679-45082015AO3331

ABSTRACTObjective:To describe the clinical aspects of cases of influenza A(H1N1)pdm09 in Brazil.Methods:A descriptive study of cases reported in Sistema de Informação de Agravos de Notificação (SINAN), 2009-2010.Results:As the final classification, we obtained 53,797 (56.79%) reported cases confirmed as a new influenza virus subtype, and 40,926 (43.21%) cases discarded. Fever was the most common sign, recorded in 99.74% of the confirmed and 98.92% of the discarded cases. Among the confirmed cases, the presence of comorbidities was reported in 32.53%, and in […]

One-year follow-up of neurological status of patients after cardiac arrest seen at the emergency room of a teaching hospital

Cássia Regina Vancini-Campanharo, Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Maria Carolina Barbosa Teixeira Lopes, Meiry Fernanda Pinto Okuno, Ruth Ester Assayag Batista, [...]

DOI: 10.1590/S1679-45082015AO3286

ABSTRACTObjective:To describe neurological status and associated factors of survivors after cardiac arrest, upon discharge, and at 6 and 12 month follow-up.Methods:A cohort, prospective, descriptive study conducted in an emergency room. Patients who suffered cardiac arrest and survived were included. A one-year consecutive sample, comprising 285 patients and survivors (n=16) followed up for one year after discharge. Neurological status was assessed by the Cerebral Performance Category before the cardiac arrest, upon discharge, and at 6 and 12 months after discharge. The […]

Characteristics of an outpatient chronic hepatitis B virus infection cohort

Danyenne Rejane de Assis, Simone de Barros Tenore, João Renato Rebello Pinho, David Salomão Lewi, Paulo Roberto Abrão Ferreira

DOI: 10.1590/S1679-45082015AO3269

ABSTRACTObjective:To characterize a chronic hepatitis B cohort based on initial and follow-up clinical evaluations.Methods:A retrospective and descriptive analysis of clinical and laboratory data from chronic HBsAg adult carriers, without HIV, unexposed to treatment, with at least two outpatient visits, between February 2006 and November 2012. Fisher´s exact test, χ², Wilcoxon, Spearman, multiple comparisons and Kappa tests were applied, the level of significance adopted was 5%, with a 95% confidence interval.Results:175 patients with mean age of 42.95±12.53 years were included: 93 […]

Check-up and cardiovascular risk progression: is there a room for innovation?

Raquel Dilguerian de Oliveira Conceição, Antonio Gabriele Laurinavicius, Nea Miwa Kashiwagi, José Antonio Maluf de Carvalho, Carlos Alberto Garcia Oliva, Raul Dias Santos Filho

DOI: 10.1590/S1679-45082015AO3216

ABSTRACTObjective:To evaluate the impact of traditional check-up appointment on the progression of the cardiovascular risk throughout time.Methods:This retrospective cohort study included 11,126 medical records of asymptomatic executives who were evaluated between January, 2005 and October, 2008. Variables included participants’ demographics characteristics, smoking habit, history of cardiovascular diseases, diabetes, dyslipidemia, total cholesterol, HDL, triglycerides, glucose, c-reactive protein, waist circumference, hepatic steatosis, Framingham score, metabolic syndrome, level of physical activity, stress, alcohol consumption, and body mass index.Results:A total of 3,150 patients was […]

Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk

Hellen Abreu da Silva, Júlia Cristina Cardoso Carraro, Josefina Bressan, Helen Hermana Miranda Hermsdorff

DOI: 10.1590/S1679-45082015AO3194

Objective To identify possible relations between serum uric acid levels and metabolic syndrome and its components in a population with cardiometabolic risk.Methods This cross-sectional study included 80 subjects (46 women), with mean age of 48±16 years, seen at the Cardiovascular Health Program.Results The prevalence of hyperuricemia and metabolic syndrome was 6.3% and 47.1%, respectively. Uric acid level was significantly higher in individuals with metabolic syndrome (5.1±1.6mg/dL), as compared to those with no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL, respectively; […]

Factors associated with functional impairment of elderly patients in the emergency departments

Maria Carolina Barbosa Teixeira Lopes, Julieth Santana Silva Lage, Cássia Regina Vancini-Campanharo, Meiry Fernanda Pinto Okuno, Ruth Ester Assayag Batista

DOI: 10.1590/S1679-45082015AO3327

ABSTRACTObjective:To assess the functional capacity of elderly patients in the emergency department as to Basic and Instrumental Activities of Daily Living.Methods:A cross-sectional study of 200 elderly patients admitted to the emergency department of a teaching hospital in São Paulo (SP), Brazil. The functional capacity of the elderly was assessed by the Katz index and Lawton & Brody scale. Statistical analyses were performed using analysis of variance, Bonferroni correction, χ2 test, or the likelihood ratio test.Results:Most seniors were independent (65%), and […]

The impact of erlotinib use in non-small-cell lung cancer patients treated in a private reference general hospital and in a private cancer clinic from 2005 to 2011

Cinthia Leite Frizzera Borges Bognar, Sergio Daniel Simon, Rene Claudio Gansl, Roberto Abramoff, Marcelo Aisen, Gilberto de Lima Lopes Junior, [...]

DOI: 10.1590/S1679-45082015AO3326

ABSTRACTObjective:To report the demographic data and clinical outcomes of non-small-cell lung cancer patients exposed to erlotinib in any line of treatment.Methods:This was a retrospective cohort study of nonsmall-cell lung cancer patients from a reference general hospital and a private oncology clinic, who received erlotinib from 2005 to 2011. Statistical analysis was performed and we evaluated demographic data and response to treatment, by correlating the results of this first cohort published in Brazil with results of current literature.Results:A total of 44 […]

Assessment of adherence to the guidelines for the management of nausea and vomiting induced by chemotherapy

Monique Sedlmaier França, Pedro Luiz Serrano Usón Junior, Yuri Philippe Pimentel Vieira Antunes, Bernard Lobato Prado, Carlos del Cistia Donnarumma, Taciana Sousa Mutão, [...]

DOI: 10.1590/S1679-45082015AO3097

ABSTRACTObjective:To assess adherence of the prescribing physicians in a private cancer care center to the American Society of Clinical Oncology guideline for antiemetic prophylaxis, in the first cycle of antineoplastic chemotherapy.Methods:A total of 139 chemotherapy regimens, of 105 patients, were evaluated retrospectively from 2011 to 2013.Results:We observed 78% of non-adherence to the guideline rate. The main disagreements with the directive were the prescription of higher doses of dexamethasone and excessive use of 5-HT3 antagonist for low risk emetogenic chemotherapy regimens. […]

Risk factors for post-extubation stridor in children: the role of orotracheal cannula

Milena Siciliano Nascimento, Cristiane Prado, Eduardo Juan Troster, Naiana Valério, Marcela Batan Alith, João Fernando Lourenço de Almeida

DOI: 10.1590/S1679-45082015AO3255

ObjectiveTo determine the risk factors associated with stridor, with special attention to the role of the cuffed orotracheal cannula.MethodsProspective analysis of all the intubated patients submitted to mechanical ventilator support from January 2008 to April 2011. The relevant factors for stridor collected were age, weight, size and type of airway tube, diagnosis, and duration of mechanical ventilation. The effects of variables on stridor were evaluated using uni- and multivariate logistic regression models.ResultsA total of 136 patients were included. Mean age […]

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