Volume 11, Number 4, October/December 2013

Mortality in a pediatric secondary-care hospital in post-conflict Liberia in 2009

Thomaz Bittencourt Couto, Sylvia Costa Lima Farhat, Tony Reid, Cláudio Schvartsman

DOI: 10.1590/S1679-45082013000400002

Objective:To describe and analyze the causes of death in a pediatric secondary-care hospital (run by Médecins sans Frontières), in Monrovia, Liberia, 6 years post-civil war, to determine the quality of care and mortality in a setting with limited resources.METHODS:Data were retrospectively collected from March 2009 to October 2009. Patient charts and laboratory records were reviewed to verify cause of death. Additionally, charts of patients aged over 1 month with an infectious cause of death were analyzed for decompensated septic shock, […]

Therapeutic touch: influence on vital signs of newborns

Nadia Christina Oliveira Ramada, Fabiane de Amorim Almeida, Mariana Lucas da Rocha Cunha

DOI: 10.1590/S1679-45082013000400003

Objective:To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit.METHODS:This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch.RESULTS:The majority of newborns […]

Assessment of posture and joint movements of the upper limbs of patients after mastectomy and lymphadenectomy

Cinira Assad Simão Haddad, Marcelo Saad, Maria del Carmen Janeiro Perez, Fausto Miranda Júnior

DOI: 10.1590/S1679-45082013000400004

Objective:To evaluate alterations in posture and range of motion of the upper limbs in women after mastectomy and lymphadenectomy, submitted to radiotherapy as adjuvant treatment.METHODS:Two groups were evaluated: 16 post-mastectomy women with lymphedema of the upper limb and 14 post-mastectomy women without lymphedema. Patients were submitted to analysis made by software, one for posture and the other to measure ranges of movement of the shoulder, elbow, and wrists. The results obtained were compared between the right and left sides, and […]

Paullinia cupana for control of hot flashes in breast cancer patients: a pilot study

Saulo Silva Oliveira, Adriana Braz del Giglio, Tatiana Goberstein Lerner, Rebecca Melo Zanellato, Livia Tiemi, Lucas Reifur, [...]

DOI: 10.1590/S1679-45082013000400005

Objective:To evaluated whether Paullinia cupana decrease number and severity of hot flashes in breast cancer survivors.METHODS:This was a prospective phase II pilot study. We studied female breast cancer survivors who had completed the cancer treatment 3 months previously and who were experiencing at least 14 hot flashes per week. At least 9 of the 15 patients were required to have a decrease of at least 50% in hot flash severity score in keeping with the Simon Design. Patients received 50mg […]

Intraoperative radiotherapy as a protocol for the treatment of initial breast cancer

Silvio Eduardo Bromberg, Rodrigo de Morais Hanriot, Afonso Celso Pinto Nazário

DOI: 10.1590/S1679-45082013000400006

Objective:To report on preliminary outcomes of single-dose intraoperative radiotherapy for early-stage breast cancer based on local recurrence rates and complications.METHODS:Fifty postmenopausal women with

Neoadjuvant chemotherapy and pathologic response: a retrospective cohort

Diocésio Alves Pinto de Andrade, Gustavo Zucca-Matthes, René Aloísio da Costa Vieira, Cristiane Thomaz de Aquino Exel de Andrade, Allini Mafra da Costa, Aurélio Julião de Castro Monteiro, [...]

DOI: 10.1590/S1679-45082013000400007

Objective:To evaluate the complete pathologic response attained by patients diagnosed with locally advanced breast cancer submitted to neoadjuvant chemotherapy based on the doxorubicin/cyclophosphamide regimen followed by paclitaxel.METHODS:A retrospective cohort of patients with locally advanced breast cancer, admitted to the Hospital de Câncer de Barretos between 2006 and 2008 submitted to the doxorubicin/cyclophosphamide protocol followed by paclitaxel (4 cycles of doxorubicin 60mg/m² and cyclophosphamide 600mg/m² every 21 days; 4 cycles of paclitaxel 175mg/m² every 21 days). The following variables were assessed: […]

How important is the number of pelvic lymph node retrieved to locorregional staging of cervix cancer?

Thales Paulo Batista, Artur Lício Rocha Bezerra, Mário Rino Martins, Vandré Cabral Gomes Carneiro

DOI: 10.1590/S1679-45082013000400008

Objective:To explore how important is the number of pelvic lymph nodes dissected for the nodal staging in FIGO IA2-IB2 cervical cancer, submitted to radical surgical treatment.METHODS:A cross-sectional study was carried out on patients who underwent Piver class II radical hysterectomy and pelvic lymphadenectomy, in two centers in the state of Pernambuco, from January, 2001 to December, 2008. The analysis of the area under the ROC curve was adopted as a summary-measure of discriminatory power of the number of nodes dissected […]

Immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenoma and non-neoplastic mucosa

Renan Brito Nogueira, Andréa Rodrigues Cordovil Pires, Thélia Maria Santos Soares, Simone Rabello de Souza Rodrigues, Mariane Antonieta Menino Campos, Giovanna Canato Toloi, [...]

DOI: 10.1590/S1679-45082013000400009

Objective:To analyze the immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenomas and non-neoplastic mucosa.METHODS:72 individuals were subjected to colonoscopy, which provided 50 samples of adenomas and 45 samples of non-neoplastic colorectal mucosa. The tissue samples were obtained via the tissue microarray technique and subjected to immunohistochemical analysis using primary anti-p53, anti-COX-2, and anti-caspase-3 antibodies. The positivity and intensity of the immunoreaction were classified. The analyzed variables were as follows: site of the adenomas in the colon, degree […]

Drug interaction in the emergency service

Meiry Fernanda Pinto Okuno, Raíssa Silveira Cintra, Cássia Regina Vancini-Campanharo, Ruth Ester Assayag Batista

DOI: 10.1590/S1679-45082013000400010

Objective:To identify the occurrence of potential drug interactions in prescriptions for adult patients admitted to the Emergency Department of Hospital São Paulo.METHODS:A cross-sectional and descriptive study. Its sample consisted of 200 medical prescriptions. The analysis of drug interactions was performed using the Drugs.com database, where they are classified according to severity of interaction as severe, moderate, mild and without interaction.RESULTS:The number of drugs in prescriptions ranged from 2 to 19, and the average per prescription was 4.97 drugs. A total […]

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