einstein (São Paulo). 01/Sep/2011;9(3):354-8.

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer

Marcelo Roberto Pereira Freitas, Sergio Daniel Simon

DOI: 10.1590/s1679-45082011ao2039

ABSTRACT
Objective:
To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX.
Methods:
A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available.
Results:
Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.091), Adjuvant! (Transbig) (K = 0.182) and National Comprehensive Cancer Network (K = 0.091). The Fisher’s exact test did not show correlation between Oncotype and standard prognostic criteria.
Conclusion:
Standard prognostic criteria showed no correlation with Oncotype DX.

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer

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